| Literature DB >> 6809024 |
P J Morrison, H J Rogers, R G Spector, I D Bradbrook, V A John.
Abstract
Pirprofen (a new non-steroidal anti-inflammatory agent), 200 mg 8 hourly, or placebo was administered orally to eight normal volunteers to investigate its effect on the pharmacokinetics and glucose and insulin responses after 1 mg i.v. glibenclamide. No significant changes were produced in these measures and in vitro studies showed no displacement of glibenclamide by pirprofen from plasma protein binding.Entities:
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Year: 1982 PMID: 6809024 PMCID: PMC1427576 DOI: 10.1111/j.1365-2125.1982.tb04949.x
Source DB: PubMed Journal: Br J Clin Pharmacol ISSN: 0306-5251 Impact factor: 4.335