Literature DB >> 680796

Modulation of the immune response by passive antibodies. IV. Effects of IgG1 and IgG2 anti-hapten antibodies.

P J Neveu, V V Micusan, A Fafard, A G Borduas.   

Abstract

The effects of IgG1 and IgG2 anti-hapten antibodies waere studied on celluar and humoral reactions induced by immunization with a hapten-carrier complex. IgG2 was shown to depress delayed hypersensitivity reactions to the carrier and to enhance anaphylactic reactions to both the hapten and the carrier whereas IgG1 appeared to have no activity except a little enhancing effect on antibody synthesis to the carrier. The regulatory role of IgG2 antibodies, which were cytophilic for macrophages, in the immune response to a hapten-carrier conjugate is discussed.

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Year:  1978        PMID： 680796      PMCID： PMC1457217     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  14 in total

1.  PREPARATION OF PURIFIED ANTI-2,4-DINITROPHENYL ANTIBODIES.

Authors:  H N EISEN
Journal:  Methods Med Res       Date:  1964

2.  Regulation of the immune response. VII. In vitro immunosuppression by F(ab') 2 or intact IgG antibodies.

Authors:  R K Lees; N R Sinclair
Journal:  Immunology       Date:  1973-04       Impact factor: 7.397

3.  Immunodeviation by passive antibody, an expression of selective immunodepression. I. Action of guinea pig IgG 1 and IgG 2 anti-hapten antibodies.

Authors:  P Vuagnat; T Neveu; G A Voisin
Journal:  Eur J Immunol       Date:  1973-02       Impact factor: 5.532

4.  Antigenic specificities of antibodies suppressing induction of delayed hypersensitivity in mice to dinitrophenylated proteins.

Authors:  K Yonemasu; A J Crowle
Journal:  Immunology       Date:  1973-10       Impact factor: 7.397

5.  The mechanism of a hapten-specific helper effect in mice.

Authors:  C A Janeway
Journal:  J Immunol       Date:  1973-10       Impact factor: 5.422

6.  Macrophage-bound antigens. I. Induction of delayed hypersensitivity and priming for production of serum antibodies in guinea pigs.

Authors:  R C Seeger; J J Oppenheim
Journal:  J Immunol       Date:  1972-08       Impact factor: 5.422

7.  Are cellular and humoral components of the immune response linked by a dispatcher cell?

Authors:  P J Neveu
Journal:  Int Arch Allergy Appl Immunol       Date:  1977

8.  Modulation of the immune response by passive antibodies. I. Anti-hapten antibodies enhanced delayed hypersensitivity to the carrier and depressed antibody synthesis to the hapten.

Authors:  P J Neveu; A G Borduas
Journal:  Int Arch Allergy Appl Immunol       Date:  1975

9.  Properties of antibodies cytophilic for macrophages.

Authors:  A Berken; B Benacerraf
Journal:  J Exp Med       Date:  1966-01-01       Impact factor: 14.307

10.  Suppression or augmentation of the antihapten response in mice by antibodies of different specificities.

Authors:  G Haughton; O Mäkelä
Journal:  J Exp Med       Date:  1973-07-01       Impact factor: 14.307
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  2 in total

1.  Marked enhancement in vivo of adjuvant activity of muramyl dipeptide to protein antigens and to synthetic weak immunogens with monoclonal anti-muramyl dipeptide antibodies.

Authors:  G M Bahr; D S Tello; L A Chedid
Journal:  Infect Immun       Date:  1985-08       Impact factor: 3.441

2.  Immunogenicity of antigen complexed with antibody. I. Role of different isotypes.

Authors:  A I Farkas; G A Medgyesi; G Füst; K Miklós; J Gergely
Journal:  Immunology       Date:  1982-03       Impact factor: 7.397
  2 in total

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