Literature DB >> 6807842

Purification and properties of anti-Trypanosoma cruzi antibodies isolated from patients with chronic Chagas' disease.

S E Hajos, C Carbonetto, R A Margni, M Esteva, E L Segura.   

Abstract

Three purified human IgG antibodies against Trypanosoma cruzi (anti-F, anti-Mc and anti-Cs) showed different reactivities in vitro. While all of them agglutinated specifically sensitized sheep red cells the complement-fixing capacity of anti-Fc and anti-Cs was higher than that of anti-Mc antibody. This one also showed a minimal precipitating activity. When the ability to neutralize mice bloodstream trypomastigotes was analyzed, the results obtained indicated that anti-F antibody was the most effective.

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Year:  1982        PMID: 6807842     DOI: 10.1016/0165-2478(82)90014-1

Source DB:  PubMed          Journal:  Immunol Lett        ISSN: 0165-2478            Impact factor:   3.685


  3 in total

1.  Agglutinating and non-agglutinating antibodies in rabbits inoculated with a particulate antigen (Salmonella typhimurium).

Authors:  R A Margni; E A Parma; S Cerone; A Erpelding; G Perdigón
Journal:  Immunology       Date:  1983-02       Impact factor: 7.397

2.  Blocking anti-Trichinella spiralis antibodies in chronically infected rats.

Authors:  S M Venturiello; S N Costantino; G H Giambartolomei
Journal:  Parasitol Res       Date:  1996       Impact factor: 2.289

3.  Interaction of purified precipitating and non-precipitating (coprecipitating) antibodies with hapten and with haptenated protein. Evidence of an asymmetric antibody molecule.

Authors:  J R Ronco; E Sciutto; J Leoni; R A Margni; R A Binaghi
Journal:  Immunology       Date:  1984-07       Impact factor: 7.397

  3 in total

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