Literature DB >> 6807714

Ergot alkaloids and phosphodiesterase; 'in vitro' activities in several rat brain areas.

P Venutti, C Ferretti, P Portaleone.   

Abstract

The 'in vitro' activity of ergotamine, dihydroergocristine, dihydroergocornine and dihydroergocryptine on the phosphodiesterase system at low and high Km in several rat brain areas was examined. These drugs were found to exert an inhibitory effect in all the areas examined with regard to both systems, and particularly on low substrate concentration phosphodiesterases.

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Year:  1982        PMID： 6807714     DOI： 10.1007/BF02327072

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

Review 1.  The role of cyclic nucleotides in central synaptic function.

Authors:  F E Bloom
Journal:  Rev Physiol Biochem Pharmacol       Date:  1975       Impact factor: 5.545

Review 2.  Dopamine receptors in the brain.

Authors:  L L Iversen
Journal:  Science       Date:  1975-06-13       Impact factor: 47.728

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  The influence of dihydroergotoxine mesylate on the low-Km phosphodiesterase of cat and rat brain in vitro.

Authors:  A Enz; P Iwangoff; A Chappuis
Journal:  Gerontology       Date:  1978       Impact factor: 5.140

Review 5.  Biochemical regulation and physiological significance of cyclic nucleotides in the nervous system.

Authors:  J W Kebabian
Journal:  Adv Cyclic Nucleotide Res       Date:  1977

6.  Effects of bromocriptine on adenylate cyclase and phosphodiesterase activities of rat striatum.

Authors:  G Pagnini; F Camanni; A Crispino; P Portaleone
Journal:  J Pharm Pharmacol       Date:  1978-02       Impact factor: 3.765

7.  Multiple cyclic nucleotide phosphodiesterase activities from rat brain.

Authors:  W J Thompson; M M Appleman
Journal:  Biochemistry       Date:  1971-01-19       Impact factor: 3.162

8.  Effect of ergot drugs on central catecholamine neurons: evidence for a stimulation of central dopamine neurons.

Authors:  H Corrodi; K Fuxe; T Hökfelt; P Lidbrink; U Ungerstedt
Journal:  J Pharm Pharmacol       Date:  1973-05       Impact factor: 3.765

9.  Bromocriptine and lisuride stimulate the accumulation of cyclic AMP in intact slices but not in homogenates of rat neostriatum.

Authors:  L Saiani; M Trabucchi; G C Tonon; P F Spano
Journal:  Neurosci Lett       Date:  1979-09       Impact factor: 3.046

10.  Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain.

Authors:  J Glowinski; L L Iversen
Journal:  J Neurochem       Date:  1966-08       Impact factor: 5.372
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  1 in total

Review 1.  Pharmacology of nootropics and metabolically active compounds in relation to their use in dementia.

Authors:  C D Nicholson
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530
  1 in total

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