Literature DB >> 6807712

Potentiation of the biological activities of daunomycin and adriamycin by ascorbic acid and dimethylsulfoxide.

M Marián, B Matkovics.   

Abstract

L-Ascorbic acid (0.57 mM) and dimethylsulfoxide (14.1 mM) were found to potentiate four times the antibacterial activities of daunomycin and adriamycin in the Staphylococcus aureus test. This effect, however, could not be demonstrated against eukaryotic cells and leukemia P 388 in mice.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6807712     DOI： 10.1007/BF02327056

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  14 in total

1.  The oxidation of ascorbate by electron affinic drugs and carcinogens.

Authors:  J E Biaglow; B Jacobson; M Varnes
Journal:  Photochem Photobiol       Date:  1978 Oct-Nov       Impact factor: 3.421

2.  The catalytic effect of the carcinogen "4-nitroquinoline-N-oxide" on the oxidation of vitamin C.

Authors:  J E Biaglow; B Jacobson; C Koch
Journal:  Biochem Biophys Res Commun       Date:  1976-06-21       Impact factor: 3.575

3.  Reducing compounds in radioprotection and radiosensitization: model experiments using ascorbic acid.

Authors:  J L Redpath; R L Willson
Journal:  Int J Radiat Biol Relat Stud Phys Chem Med       Date:  1973-01

4.  Lethal action and metabolic effects of streptonigrin on Escherichia coli.

Authors:  H L White; J R White
Journal:  Mol Pharmacol       Date:  1968-11       Impact factor: 4.436

5.  The interaction of hydroxyl radicals with dimethylsulfoxide produces formaldehyde.

Authors:  S M Klein; G Cohen; A I Cederbaum
Journal:  FEBS Lett       Date:  1980-07-28       Impact factor: 4.124

6.  Combination chemoprevention of cancer.

Authors:  M B Sporn
Journal:  Nature       Date:  1980-09-11       Impact factor: 49.962

7.  NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals.

Authors:  N R Bachur; S L Gordon; M V Gee; H Kon
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

8.  Binding specificity of chemically and enzymatically activated anthracycline anticancer agents to nucleic acids.

Authors:  B K Sinha
Journal:  Chem Biol Interact       Date:  1980-04       Impact factor: 5.192

9.  Enzymatic defenses of the mouse heart against reactive oxygen metabolites: alterations produced by doxorubicin.

Authors:  J H Doroshow; G Y Locker; C E Myers
Journal:  J Clin Invest       Date:  1980-01       Impact factor: 14.808

10.  Resistance to adriamycin cytotoxicity among respiratory-deficient mutants in yeast.

Authors:  S C Hixon; A Ocak; J E Thomas; J P Daugherty
Journal:  Antimicrob Agents Chemother       Date:  1980-03       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.