Literature DB >> 6807601

Mutational events in mouse myeloma cells.

S L Morrison, M D Scharff.   

Abstract

Cultured mouse myeloma cells frequently generate variants in immunoglobulin expression and structure. In this paper the authors will review the phenotypes of the variants which have been identified and discuss the mechanisms which may be responsible for the somatic instability of the immunoglobulin genes in mouse myeloma cells.

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Year:  1981        PMID: 6807601

Source DB:  PubMed          Journal:  Crit Rev Immunol        ISSN: 1040-8401            Impact factor:   2.214


  12 in total

1.  Ectopic recombination within homologous immunoglobulin mu gene constant regions in a mouse hybridoma cell line.

Authors:  M D Baker; L R Read
Journal:  Mol Cell Biol       Date:  1992-10       Impact factor: 4.272

Review 2.  Engineering soluble major histocompatibility molecules: why and how.

Authors:  D H Margulies; R Lopez; L F Boyd; J McCluskey
Journal:  Immunol Res       Date:  1987       Impact factor: 2.829

3.  Molecular analysis of membrane immunoglobulin-negative variants.

Authors:  H A Irick; R W Andrews; I H Yang; R A Blanton; C H Sibley
Journal:  Immunogenetics       Date:  1986       Impact factor: 2.846

4.  Identification of mutant monoclonal antibodies with increased antigen binding.

Authors:  R R Pollock; D L French; M L Gefter; M D Scharff
Journal:  Proc Natl Acad Sci U S A       Date:  1988-04       Impact factor: 11.205

Review 5.  Mutations that influence the secretory path in animal cells.

Authors:  A M Tartakoff
Journal:  Biochem J       Date:  1983-10-15       Impact factor: 3.857

6.  Nucleotide sequences of immunoglobulin mu heavy chain deletion mutants.

Authors:  W O Baczynsky; S Sugii; H Murialdo; N Pennell; C Filkin; N Hozumi; M J Shulman
Journal:  Nucleic Acids Res       Date:  1983-11-11       Impact factor: 16.971

7.  Biochemical characterization of mIgM- variants of the murine B-cell lymphoma, WEHI 279.1.

Authors:  C H Sibley; R Andrews-Wagner
Journal:  Immunogenetics       Date:  1983       Impact factor: 2.846

8.  Transmission blockade of Plasmodium falciparum malaria by anti-Pfs230-specific antibodies is isotype dependent.

Authors:  W Roeffen; F Geeraedts; W Eling; P Beckers; B Wizel; N Kumar; T Lensen; R Sauerwein
Journal:  Infect Immun       Date:  1995-02       Impact factor: 3.441

9.  Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse.

Authors:  B Baumann; M J Potash; G Köhler
Journal:  EMBO J       Date:  1985-02       Impact factor: 11.598

10.  Generation and analysis of random point mutations in an antibody CDR2 sequence: many mutated antibodies lose their ability to bind antigen.

Authors:  C Chen; V A Roberts; M B Rittenberg
Journal:  J Exp Med       Date:  1992-09-01       Impact factor: 14.307

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