Literature DB >> 6807337

A study of ultrastructural alterations in experimental non-A, non-B hepatitis by electron-beam analysis.

T F McCaul, K N Tsiquaye, G Tovey, C Hames, X Z Lu, D N Hogben, A J Zuckerman.   

Abstract

An electron-beam X-ray microanalysis was carried out on sections of liver biopsy specimens obtained from chimpanzees infected with non-A, non-B hepatitis. The microanalysis was concentrated over areas where typical derangement of the endoplasmic reticulum, with the formation of tubular forms possessing walls with electron-dense central membrane, was visualized. These tubular structures are regarded as the most notable pathological alteration in affected hepatocytes. However, the electron-probe microanalysis showed no deviation of the energy spectrum when compared with the background or control analysis.

Entities:  

Mesh：

Year:  1982        PMID： 6807337      PMCID： PMC2040622     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  9 in total

1.  Potassium permanganate staining of ultrathin sections for electron microscopy.

Authors:  J S Sutton
Journal:  J Ultrastruct Res       Date:  1967-12

2.  Acute non-A, non-B hepatitis: specific ultrastructural alterations in endoplasmic reticulum of infected hepatocytes.

Authors:  D Jackson; E Tabor; R J Gerety
Journal:  Lancet       Date:  1979-06-09       Impact factor: 79.321

3.  Application of electron microscopy to the study of structural changes in the liver in non-A, non-B hepatitis.

Authors:  T F McCaul; K N Tsiquaye; G Tovey; C Hames; A J Zuckerman
Journal:  J Virol Methods       Date:  1982-03       Impact factor: 2.014

4.  Ultrastructural changes and virus-like particles localized in liver hepatocytes of chimpanzees infected with non-A, non-B hepatitis.

Authors:  K H Burk; G A Cabral; G R Dreesman; R L Peters; H J Alter
Journal:  J Med Virol       Date:  1981       Impact factor: 2.327

5.  Non-A, non-B hepatitis: ultrastructural evidence for two agents in experimentally infected chimpanzees.

Authors:  Y K Shimizu; S M Feinstone; R H Purcell; H J Alter; W T London
Journal:  Science       Date:  1979-07-13       Impact factor: 47.728

6.  Non-A/non-B hepatitis in experimentally infected chimpanzees: cross-challenge and electron microscopic studies.

Authors:  D W Bradley; J E Maynard; E H Cook; J W Ebert; C R Gravelle; K N Tsiquaye; H Kessler; A J Zuckerman; M F Miller; C Ling; L R Overby
Journal:  J Med Virol       Date:  1980       Impact factor: 2.327

7.  Ultrastructural changes in the liver in experimental non-A, non-B hepatitis.

Authors:  K N Tsiquaye; S Amini; H Kessler; R G Bird; G Tovey; A J Zuckerman
Journal:  Br J Exp Pathol       Date:  1981-02

8.  Further evidence of cellular changes associated with non-A, non-B hepatitis.

Authors:  K N Tsiquaye; R G Bird; G Tovey; R J Wyke; R Williams; A J Zuckerman
Journal:  J Med Virol       Date:  1980       Impact factor: 2.327

9.  Viruslike particles in a plasma fraction (fibrinogen) and in the circulation of apparently healthy blood donors capable of inducing non-A/non-B hepatitis in humans and chimpanzees.

Authors:  H Yoshizawa; Y Akahane; Y Itoh; S Iwakiri; K Kitajima; M Morita; A Tanaka; T Nojiri; M Shimizu; Y Miyakawa; M Mayumi
Journal:  Gastroenterology       Date:  1980-09       Impact factor: 22.682
  9 in total

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