Literature DB >> 6806562

The effect of chlorpromazine on transformation in Bacillus subtilis.

H Mooibroek, G Venema.   

Abstract

In the presence of the widely used tranquilizer, chlorpromazine, transforming DNA of Bacillus subtilis is photoinactivated by long-wave ultraviolet light. The loss of biological activity is predominantly caused by lack of binding of the DNA to recipient cells and the introduction of single-strand breaks in the treated DNA.

Entities:  

Mesh:

Substances:

Year:  1982        PMID: 6806562     DOI: 10.1007/BF00333808

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN: 0026-8925


  15 in total

1.  Sedimentation rate as a measure of molecular weight of DNA.

Authors:  E BURGI; A D HERSHEY
Journal:  Biophys J       Date:  1963-07       Impact factor: 4.033

2.  INTERACTION OF THE RADICAL ION OF CHLORPROMAZINE WITH DEOXYRIBONUCLEIC ACID.

Authors:  S I OHNISHI; H M MCCONNELL
Journal:  J Am Chem Soc       Date:  1965-05-20       Impact factor: 15.419

3.  Shape of ultra-violet inactivation curves of transforming deoxyribonucleic acid.

Authors:  C S RUPERT; S H GOODGAL
Journal:  Nature       Date:  1960-02-20       Impact factor: 49.962

4.  Photosensitization by drugs.

Authors:  D E Moore
Journal:  J Pharm Sci       Date:  1977-09       Impact factor: 3.534

5.  Transformation and DNA size. I. Activity of fragments of defined size and a fit to a random double cross-over model.

Authors:  A Cato; W R Guild
Journal:  J Mol Biol       Date:  1968-10-14       Impact factor: 5.469

6.  Transformation in bacillus subtilis: fate of transforming DNA in transformation deficient mutants.

Authors:  J Buitenwerf; G Venema
Journal:  Mol Gen Genet       Date:  1977-03-07

7.  Ultraviolet inactivation and excision-repair in Bacillus subtilis. 3. Sensitized photoinactivation of transforming DNA, and the effect of thymine dimers on differential marker inactivation and differential marker repair.

Authors:  S Bron; G Venema
Journal:  Mutat Res       Date:  1972-08       Impact factor: 2.433

8.  Photomutagenesis by chlorinated phenothiazine tranquilizers.

Authors:  J G Jose
Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

9.  7-HYDROXYCHLORPROMAZINE: POTENTIAL TOXIC DRUG METABOLITE IN PSYCHIATRIC PATIENTS.

Authors:  T L PERRY; C F CULLING; K BERRY; S HANSEN
Journal:  Science       Date:  1964-10-02       Impact factor: 47.728

10.  Integration of deoxyribonuclease-treated DNA in bacillus subtilis transformation.

Authors:  W F Bodmer
Journal:  J Gen Physiol       Date:  1966-07       Impact factor: 4.086

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.