Literature DB >> 6806287

Site of action of a ribosomal RNA methylase conferring resistance to thiostrepton.

J Thompson, F Schmidt, E Cundliffe.   

Abstract

A methylase enzyme, responsible for autoimmunity in the thiostrepton producer Streptomyces azureus, renders ribosomes completely resistant to thiostrepton. This RNA-pentose methylase modifies adenosine-1067 of Escherichia coli 23 S rRNA.

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Year:  1982        PMID: 6806287

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  42 in total

Review 1.  Office of Naval Research lecture. Antibiotics and the search for new principles.

Authors:  E Cundliffe
Journal:  J Ind Microbiol       Date:  1991-04

2.  Isolation and characterization of the gene cluster for biosynthesis of the thiopeptide antibiotic TP-1161.

Authors:  Kerstin Engelhardt; Kristin F Degnes; Sergey B Zotchev
Journal:  Appl Environ Microbiol       Date:  2010-09-17       Impact factor: 4.792

Review 3.  Avoidance of suicide in antibiotic-producing microbes.

Authors:  Eric Cundliffe; Arnold L Demain
Journal:  J Ind Microbiol Biotechnol       Date:  2010-05-06       Impact factor: 3.346

4.  Alpha-sarcin cleavage of ribosomal RNA is inhibited by the binding of elongation factor G or thiostrepton to the ribosome.

Authors:  S P Miller; J W Bodley
Journal:  Nucleic Acids Res       Date:  1991-04-11       Impact factor: 16.971

5.  A chemical interference study on the interaction of ribosomal protein L11 from Escherichia coli with RNA molecules containing its binding site from 23S rRNA.

Authors:  D Karaoglu; D L Thurlow
Journal:  Nucleic Acids Res       Date:  1991-10-11       Impact factor: 16.971

Review 6.  Molecular mechanisms of drug resistance.

Authors:  J D Hayes; C R Wolf
Journal:  Biochem J       Date:  1990-12-01       Impact factor: 3.857

Review 7.  Structural biological study of self-resistance determinants in antibiotic-producing actinomycetes.

Authors:  Masanori Sugiyama
Journal:  J Antibiot (Tokyo)       Date:  2015-04-15       Impact factor: 2.649

8.  Nucleotide sequence and determination of the extremities of the 26S ribosomal RNA gene in wheat mitochondria: evidence for sequence rearrangements in the ribosomal genes of higher plants.

Authors:  D Falconet; M Sevignac; F Quétier
Journal:  Curr Genet       Date:  1988       Impact factor: 3.886

9.  A Family Divided: Distinct Structural and Mechanistic Features of the SpoU-TrmD (SPOUT) Methyltransferase Superfamily.

Authors:  Aiswarya Krishnamohan; Jane E Jackman
Journal:  Biochemistry       Date:  2018-12-03       Impact factor: 3.162

10.  Structure of the thiostrepton resistance methyltransferase.S-adenosyl-L-methionine complex and its interaction with ribosomal RNA.

Authors:  Mark S Dunstan; Pei C Hang; Natalia V Zelinskaya; John F Honek; Graeme L Conn
Journal:  J Biol Chem       Date:  2009-04-15       Impact factor: 5.157

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