Literature DB >> 680592

Sialic acids of human large bowel mucosa: o-acylated variants in normal and malignant states.

C M Rogers, K B Cooke, M I Filipe.   

Abstract

Five sialic acid variants have been demonstrated in normal, 'transitional', and tumour extracts of human large bowel mucosa by thin-layer chromatography. Two-dimensional thin-layer chromatography, with intermediate alkaline hydrolysis, confirmed that the variants were N-acetyl neuraminic acids with additional O-acylation. Cases studied so far show changes in the proportions of these variants in malignancy.

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Year:  1978        PMID： 680592      PMCID： PMC1412088          DOI： 10.1136/gut.19.7.587

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  9 in total

1.  The demonstration of O-acetylated sialic acids in colonic epithelial glycoproteins.

Authors:  P E Reid; C F Culling; W C Tsang; M G Clay; C W Ramey; W L Dunn
Journal:  Can J Biochem       Date:  1975-03

2.  [Occurrence and determination of neuraminic acid in the blood].

Authors:  P BOHM; S DAUBER; L BAUMEISTER
Journal:  Klin Wochenschr       Date:  1954-04-01

3.  Value of histochemical reactions for mucosubstances in the diagnosis of certain pathological conditions of the colon and rectum.

Authors:  M I Filipe
Journal:  Gut       Date:  1969-07       Impact factor: 23.059

4.  Characterization of human colonic mucoprotein antigen.

Authors:  D V Gold; F Miller
Journal:  Immunochemistry       Date:  1974-07

5.  Changes in composition of mucin in the mucosa adjacent to carcinoma of the colon as compared with the normal: a biochemical investigation.

Authors:  M I Filipe; K B Cooke
Journal:  J Clin Pathol       Date:  1974-04       Impact factor: 3.411

6.  Cell differentiation and the development of colonic neoplasms.

Authors:  M Lipkin; E Deschner; F Troncale
Journal:  Gastroenterology       Date:  1970-08       Impact factor: 22.682

Review 7.  Mucin histochemistry of the colon.

Authors:  M I Filipe; A C Branfoot
Journal:  Curr Top Pathol       Date:  1976

8.  The value of a study of the mucosubstances in rectal biopsies from patients with carcinoma of the rectum and lower sigmoid in the diagnosis of premalignant mucosa.

Authors:  M I Filipe
Journal:  J Clin Pathol       Date:  1972-02       Impact factor: 3.411

9.  New sialic acids. Identification of N-glycoloyl-O-acetylneuraminic acids and N-acetyl-O-glycoloylneuraminic acids by improved methods for detection of N-acyl and O-acyl groups and by gas-liquid chromatography.

Authors:  H P Buscher; J Casals-Stenzel; R Schaufer
Journal:  Eur J Biochem       Date:  1974-12-16
  9 in total
  18 in total

1.  Mucin histochemistry of virus-induced duodenal adenomas in guinea fowl.

Authors:  I Toshkov; T Kirev
Journal:  J Cancer Res Clin Oncol       Date:  1990       Impact factor: 4.553

Review 2.  Mucin histochemistry in colorectal disease: principles and potential clinical applications.

Authors:  W V Bogomoletz
Journal:  Int J Colorectal Dis       Date:  1986-10       Impact factor: 2.571

3.  Failure to demonstrate specificity of the morphological and histochemical changes in mucosa adjacent to colonic carcinoma.

Authors:  A C Branfoot; M I Filipe
Journal:  J Clin Pathol       Date:  1979-08       Impact factor: 3.411

Review 4.  The relevance of the histochemistry of colonic mucins based upon their PAS reactivity.

Authors:  C F Culling; P E Reid; W L Dunn; H J Freeman
Journal:  Histochem J       Date:  1981-11

5.  Chemical and histochemical studies of normal and diseased human gastrointestinal tract. II. A comparison between histologically normal small intestine and Crohn's disease of the small intestine.

Authors:  P E Reid; C F Culling; W L Dunn; M G Clay
Journal:  Histochem J       Date:  1984-03

6.  Histochemical characteristics of mucins in the small intestine. A comparative study of normal mucosa, benign epithelial tumours and carcinoma.

Authors:  M I Filipe; C Fenger
Journal:  Histochem J       Date:  1979-05

7.  Chemical and histochemical studies of normal and diseased human gastrointestinal tract. III. Changes in the histochemical and chemical properties of the epithelial glycoproteins in the mucosa close to colonic tumours.

Authors:  P E Reid; D A Owen; W L Dunn; C W Ramey; D A Lazosky; M G Clay
Journal:  Histochem J       Date:  1985-02

8.  Colorectal goblet cell sialomucin heterogeneity: its relation to malignant disease.

Authors:  K Sugihara; J R Jass
Journal:  J Clin Pathol       Date:  1986-10       Impact factor: 3.411

9.  The roles of enteric bacterial sialidase, sialate O-acetyl esterase and glycosulfatase in the degradation of human colonic mucin.

Authors:  A P Corfield; S A Wagner; L J O'Donnell; P Durdey; R A Mountford; J R Clamp
Journal:  Glycoconj J       Date:  1993-02       Impact factor: 2.916

10.  Chemical and histochemical studies of normal and diseased human gastrointestinal tract. I. A comparison between histologically normal colon, colonic tumours, ulcerative colitis and diverticular disease of the colon.

Authors:  P E Reid; C F Culling; W L Dunn; C W Ramey; M G Clay
Journal:  Histochem J       Date:  1984-03
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