Literature DB >> 6805426

In vitro comparison of N-formimidoyl thienamycin (MK0787) and Azlocillin with three aminoglycosides and ticarcillin against Pseudomonas aeruginosa.

A J Matzkowitz, A L Baltch, R P Smith, N T Sutphen, M C Hammer, J V Conroy.   

Abstract

The activities of N-formimidoyl thienamycin and azlocillin were compared with those of tobramycin, gentamicin, amikacin, and ticarcillin against 175 Pseudomonas aeruginosa isolates, including 24 strains with known mechanisms of resistance to aminoglycosides. The 50% mean inhibitory concentration for azlocillin was lower than for ticarcillin, but the 90% mean inhibitory concentration was similar for both drugs. All susceptible and multidrug-resistant strains were susceptible to N-formimidoyl thienamycin.

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Year:  1982        PMID： 6805426      PMCID： PMC181971          DOI： 10.1128/AAC.21.4.685

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  Agar disk diffusion susceptibility characteristics of azlocillin, carbenicillin, mezlocillin, piperacillin, and ticarcillin.

Authors:  D Phaneuf; H C Neu
Journal:  Antimicrob Agents Chemother       Date:  1979-11       Impact factor: 5.191

2.  [Azlocillin--a new penicillin against Pseudomonas aeruginosa and other gram-negative bacteria].

Authors:  H B König; K G Metzger; R P Mürmann; H A Offe; P Schacht; W Schröck
Journal:  Infection       Date:  1977       Impact factor: 3.553

3.  Pseudomonas aeruginosa bacteremia: a clinical study of 75 patients.

Authors:  A L Baltch; P E Griffin
Journal:  Am J Med Sci       Date:  1977 Sep-Oct       Impact factor: 2.378

4.  Activity of azlocillin and mezlocillin against gram-negative organisms: comparison with other penicillins.

Authors:  R Wise; A P Gillett; J M Andrews; K A Bedford
Journal:  Antimicrob Agents Chemother       Date:  1978-04       Impact factor: 5.191

5.  Pseudomonas aeruginosa bacteremia: susceptibility of 100 blood culture isolates to seven antimicrobial agents and its clinical significance.

Authors:  A L Baltch; M Hammer; R P Smith; N Sutphen
Journal:  J Lab Clin Med       Date:  1979-08

6.  Comparative study of anti-pseudomonas activity of azlocillin, mezlocillin, and ticarcillin.

Authors:  L Coppens; J Klastersky
Journal:  Antimicrob Agents Chemother       Date:  1979-03       Impact factor: 5.191

7.  Pseudomonas bacteremia. Review of 108 cases.

Authors:  M R Flick; L E Cluff
Journal:  Am J Med       Date:  1976-04       Impact factor: 4.965

8.  Azlocillin and mezlocillin: new ureido penicillins.

Authors:  K P Fu; H C Neu
Journal:  Antimicrob Agents Chemother       Date:  1978-06       Impact factor: 5.191

9.  MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities.

Authors:  H Kropp; J G Sundelof; J S Kahan; F M Kahan; J Birnbaum
Journal:  Antimicrob Agents Chemother       Date:  1980-06       Impact factor: 5.191

10.  In vitro activity of N-formimidoyl thienamycin (MK0787), a crystalline derivative of thienamycin.

Authors:  V W Horadam; J D Smilack; C L Montgomery; J Werringloer
Journal:  Antimicrob Agents Chemother       Date:  1980-10       Impact factor: 5.191
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  3 in total

Review 1.  In vitro activity of imipenem--a review.

Authors:  I Braveny
Journal:  Eur J Clin Microbiol       Date:  1984-10       Impact factor: 3.267

2.  In vitro comparison of Pseudomonas aeruginosa isolates with various susceptibilities to aminoglycosides and ten beta-lactam antibiotics.

Authors:  D H Wu; A L Baltch; R P Smith
Journal:  Antimicrob Agents Chemother       Date:  1984-04       Impact factor: 5.191

Review 3.  Imipenem/cilastatin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy.

Authors:  S P Clissold; P A Todd; D M Campoli-Richards
Journal:  Drugs       Date:  1987-03       Impact factor: 9.546
  3 in total

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