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Literature DB >> 6805381

Acetohydroxy acid synthase isoenzymes of Escherichia coli K12 and Salmonella typhimurium.

M de Felice, C T Lago, C H Squires, J M Calvo.

Abstract

In Escherichia coli K12 and in Salmonella typhimurium the first step common to the biosynthesis of isoleucine, leucine and valine is catalyzed by an intriguing system of isoenzymes. Two of these are normally expressed, while the genetic determinant for a third one is transcribed, but not translated as an active polypeptide. We analyze here the significance of this system in the light of the most recent results.

Entities: Chemical Species

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Year: 1982 PMID： 6805381

Source DB: PubMed Journal: Ann Microbiol (Paris) ISSN： 0300-5410

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Cited

25 in total

1. ilvIH operon expression in Escherichia coli requires Lrp binding to two distinct regions of DNA.

Authors: Samina Jafri; Shaolin Chen; Joseph M Calvo
Journal: J Bacteriol Date: 2002-10 Impact factor: 3.490

2. In vitro transcription from the Escherichia coli ilvIH promoter.

Authors: D A Willins; J M Calvo
Journal: J Bacteriol Date: 1992-12 Impact factor: 3.490

3. Pleiotropic effects of poxA regulatory mutations of Escherichia coli and Salmonella typhimurium, mutations conferring sulfometuron methyl and alpha-ketobutyrate hypersensitivity.

Authors: T K Van Dyk; D R Smulski; Y Y Chang
Journal: J Bacteriol Date: 1987-10 Impact factor: 3.490

Acetohydroxy acid synthase isoenzymes of Escherichia coli K12 and Salmonella typhimurium.

1. ilvIH operon expression in Escherichia coli requires Lrp binding to two distinct regions of DNA.

2. In vitro transcription from the Escherichia coli ilvIH promoter.

3. Pleiotropic effects of poxA regulatory mutations of Escherichia coli and Salmonella typhimurium, mutations conferring sulfometuron methyl and alpha-ketobutyrate hypersensitivity.

4. Nucleotide sequence of the yeast ILV2 gene which encodes acetolactate synthase.

5. The ilvIH operon of Escherichia coli is positively regulated.

6. Unusual organization of the ilvIH promoter of Escherichia coli.

7. Mutations affecting the ability of Escherichia coli Lrp to bind DNA, activate transcription, or respond to leucine.

Review 8. The leucine-responsive regulatory protein, a global regulator of metabolism in Escherichia coli.

9. Sulfometuron methyl-sensitive and -resistant acetolactate synthases of the archaebacteria Methanococcus spp.

10. Physiological implications of the specificity of acetohydroxy acid synthase isozymes of enteric bacteria.