Literature DB >> 6805018

The effect of repeated electroconvulsive shocks on growth hormone secretion and growth hormone responses to clonidine in the intact rat.

J A Steiner, G Evans, D G Grahame-Smith.   

Abstract

The effect of repeated electroconvulsive shocks (ECS) on growth hormone (GH) secretion was studied in rats. Male Sprague-Dawley animals were given one ECS daily for 10 days under halothane anaesthesia. Control animals were anaesthetised only. GH secretion was studied 24 h after the last ECS or sham procedure. Background GH secretion was significantly greater in ECS-treated than in sham-treated animals (P less than 0.001). The GH response to IV clonidine (0.01--0.1 mg/kg) did not differ between the two groups. The size of the GH response was not directly related to the basal GH secretion and could not be explained in terms of it.

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Year:  1982        PMID： 6805018     DOI： 10.1007/BF00430767

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  15 in total

1.  Repeated electroconvulsive shock increases the behavioural responses of rats to injection of both dopamine and dibutyryl cyclic AMP into the nucleus accumbens.

Authors:  D J Heal; A R Green
Journal:  Neuropharmacology       Date:  1978-12       Impact factor: 5.250

2.  Electroconvulsive shock and postsynaptic catecholamine effects: increased psychomotor stimulant action of apomorphine and clonidine in reserpine pretreated mice by repeated ECS.

Authors:  K Modigh
Journal:  J Neural Transm       Date:  1975       Impact factor: 3.575

3.  Further observations on the effect of repeated electroconvulsive shock on the behavioural responses of rats produced by increases in the functional activity of brain 5-hydroxytryptamine and dopamine.

Authors:  A R Green; D J Heal; D G Grahame-Smith
Journal:  Psychopharmacology (Berl)       Date:  1977-04-29       Impact factor: 4.530

4.  Effects of apomorphine and clonidine on rat plasma growth hormone after pretreatment with reserpine and electroconvulsive shocks.

Authors:  S Edén; K Modigh
Journal:  Brain Res       Date:  1977-07-01       Impact factor: 3.252

5.  Electroconvulsive shock increases the behavioural responses of rats to brain 5-hydroxytryptamine accumulation and central nervous system stimulant drugs.

Authors:  J P Evans; D G Grahame-Smith; A R Green; A F Tordoff
Journal:  Br J Pharmacol       Date:  1976-02       Impact factor: 8.739

6.  Long-term effects of electroconvulsive shock therapy on synthesis, turnover and uptake of brain monoamines.

Authors:  K Modigh
Journal:  Psychopharmacology (Berl)       Date:  1976-09-17       Impact factor: 4.530

7.  Effects of electroconvulsive treatment on growth hormone secretion induced by monoamine receptor agonists in reserpine-pretreated rats.

Authors:  J Balldin; P Bolle; S Edén; E Eriksson; K Modigh
Journal:  Psychoneuroendocrinology       Date:  1980-12       Impact factor: 4.905

8.  A neuroendocrine study of the mechanism of action of ECT.

Authors:  A P Slade; S A Checkley
Journal:  Br J Psychiatry       Date:  1980-09       Impact factor: 9.319

9.  Effect of clonidine on growth hormone, prolactin, luteinizing hormone, follicle-stimulating hormone, and thyroid-stimulating hormone in the serum of normal men.

Authors:  S Lal; G Tolis; S B Martin; G M Brown; H Guyda
Journal:  J Clin Endocrinol Metab       Date:  1975-11       Impact factor: 5.958

10.  Electric convulsion therapy in depression: a double-blind controlled trial.

Authors:  E D West
Journal:  Br Med J (Clin Res Ed)       Date:  1981-01-31
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