Literature DB >> 6804636

Immunologic evaluation of patients with polychlorinated biphenyl poisoning: evaluation of delayed-type skin hypersensitive response and its relation to clinical studies.

K J Chang, K H Hsieh, S Y Tang, T C Tung, T P Lee.   

Abstract

Polychlorinated biphenyl (PCB) poisoning causes many physiological abnormalities including immune suppression. Cellular immunity was studied in 30 PCB-poisoned patients and 50 normal human subjects. PCB poisoning caused suppression of cellular immunity such as the delayed-type skin response to streptokinase and streptodornase. The suppression of cellular immunity was correlated with the severity of the disease. Thus evaluation of the immune function may be helpful for the diagnosis of PCB poisoning.

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Year:  1982        PMID： 6804636     DOI： 10.1080/15287398209530156

Source DB:  PubMed          Journal:  J Toxicol Environ Health        ISSN： 0098-4108


  11 in total

Review 1.  Immunotoxicology: suppressive and stimulatory effects of drugs and environmental chemicals on the immune system. A discussion.

Authors:  E Gleichmann; I Kimber; I F Purchase
Journal:  Arch Toxicol       Date:  1989       Impact factor: 5.153

2.  Effect of dam's accumulated tissue PCBs on mouse filial T-cell population and T-cell subpopulations.

Authors:  Y Takagi; S Aburada; T Otake; N Ikegami
Journal:  Bull Environ Contam Toxicol       Date:  1989-03       Impact factor: 2.151

3.  Lack of direct immunosuppressive effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on human peripheral blood lymphocyte subsets in vitro.

Authors:  D S Lang; S Becker; G C Clark; R B Devlin; H S Koren
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153

Review 4.  Approaches to detecting immunotoxic effects of environmental contaminants in humans.

Authors:  H Tryphonas
Journal:  Environ Health Perspect       Date:  2001-12       Impact factor: 9.031

5.  Effect of prenatal exposure to polychlorinated biphenyls on incidence of acute respiratory infections in preschool Inuit children.

Authors:  Frédéric Dallaire; Eric Dewailly; Carole Vézina; Gina Muckle; Jean-Philippe Weber; Suzanne Bruneau; Pierre Ayotte
Journal:  Environ Health Perspect       Date:  2006-08       Impact factor: 9.031

6.  Contaminant-related suppression of delayed-type hypersensitivity and antibody responses in harbor seals fed herring from the Baltic Sea.

Authors:  P S Ross; R L De Swart; P J Reijnders; H Van Loveren; J G Vos; A D Osterhaus
Journal:  Environ Health Perspect       Date:  1995-02       Impact factor: 9.031

7.  Acute infections and environmental exposure to organochlorines in Inuit infants from Nunavik.

Authors:  Frédéric Dallaire; Eric Dewailly; Gina Muckle; Carole Vézina; Sandra W Jacobson; Joseph L Jacobson; Pierre Ayotte
Journal:  Environ Health Perspect       Date:  2004-10       Impact factor: 9.031

8.  Lipopolysaccharide-induced hepatic injury is enhanced by polychlorinated biphenyls.

Authors:  A P Brown; A E Schultze; W L Holdan; J P Buchweitz; R A Roth; P E Ganey
Journal:  Environ Health Perspect       Date:  1996-06       Impact factor: 9.031

9.  Respiratory involvement and immune status in yusho patients.

Authors:  Y Nakanishi; N Shigematsu; Y Kurita; K Matsuba; H Kanegae; S Ishimaru; Y Kawazoe
Journal:  Environ Health Perspect       Date:  1985-02       Impact factor: 9.031

10.  Decreased lymphocyte responses in free-ranging bottlenose dolphins (Tursiops truncatus) are associated with increased concentrations of PCBs and DDT in peripheral blood.

Authors:  G P Lahvis; R S Wells; D W Kuehl; J L Stewart; H L Rhinehart; C S Via
Journal:  Environ Health Perspect       Date:  1995-05       Impact factor: 9.031
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