Literature DB >> 6803979

Side effects of benoxaprofen.

C Hindson, T Daymond, B Diffey, F Lawlor.   

Abstract

A study was made of adverse dermatological reactions to the non-steroidal anti-inflammatory agent benoxaprofen. Photosensitivity was seen in several patients, confined to wavelengths less than 340 nm. Other cutaneous side effects were erythema multiforme, the Stevens-Johnson syndrome, milia, and onycholysis. One case of pancytopenia and toxic epidermal necrolysis was reported. patients were not rechallenged with the drug, but these reactions appear to be true side effects of benoxaprofen.

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Year:  1982        PMID: 6803979      PMCID: PMC1498237          DOI: 10.1136/bmj.284.6326.1368

Source DB:  PubMed          Journal:  Br Med J (Clin Res Ed)        ISSN: 0267-0623


  2 in total

1.  Association between Stevens-Johnson syndrome and benoxaprofen.

Authors:  A E Taylor; D Goff; T C Hindson
Journal:  Br Med J (Clin Res Ed)       Date:  1981-05-02

2.  Long-term safety of benoxaprofen.

Authors:  W M Mikulaschek
Journal:  J Rheumatol Suppl       Date:  1980
  2 in total
  8 in total

1.  Lack of photosensitising potential of tenidap, a novel anti-rheumatic agent.

Authors:  J Ferguson; M R Leeming
Journal:  Br J Clin Pharmacol       Date:  1995       Impact factor: 4.335

Review 2.  New drugs. Adverse reactions. I.

Authors:  D N Bateman; S Chaplin
Journal:  Br Med J (Clin Res Ed)       Date:  1988-03-12

3.  Benoxaprofen.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1982-08-14

4.  Benoxaprofen: effect on cutaneous lesions in psoriasis.

Authors:  B R Allen; S M Littlewood
Journal:  Br Med J (Clin Res Ed)       Date:  1982-10-30

5.  Melanoma diagnosed 27 years after a benoxaprofen-induced photosensitivity reaction.

Authors:  Kuen Yeow Chin; Bara El-Kayat; Alistair Milne; Andrew Hart
Journal:  J Dermatol Case Rep       Date:  2012-03-27

Review 6.  Drug-induced cholestasis.

Authors:  H J Zimmerman; J H Lewis
Journal:  Med Toxicol       Date:  1987 Mar-Apr

7.  Experimental studies on the mechanism of benoxaprofen photoreactions.

Authors:  B Ljunggren; M Bjellerup; H Möller
Journal:  Arch Dermatol Res       Date:  1983       Impact factor: 3.017

8.  Computational Studies of the Photodegradation Mechanism of the Highly Phototoxic Agent Benoxaprofen.

Authors:  Klefah A K Musa; Leif A Eriksson
Journal:  ACS Omega       Date:  2022-08-11
  8 in total

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