Literature DB >> 6803773

Secondary structures of hyaluronate and chondroitin sulphates. A 1H n.m.r. study of NH signals in dimethyl sulphoxide solution.

J E Scott, F Heatley, D Moorcroft, A H Olavesen.   

Abstract

1H n.m.r. spectra in [2H6]dimethyl sulphoxide of dodecyltrimethylammonium salts of chondroitin sulphates and hyaluronate, or sodium salts of oligomers from hyaluronate, showed unambiguous NH signals. The acetamido NH occurs in two different environments: environment I ('normal') in simple sugars, and environment II (hydrogen-bonded NH) appearing in tri- or tetrasaccharides, indicating a secondary structure in hyaluronate (and some chondroitin sulphates) involving a hydrogen-bonded acetamido NH.

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Year:  1981        PMID： 6803773      PMCID： PMC1163443          DOI： 10.1042/bj1990829

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  9 in total

1.  A modified uronic acid carbazole reaction.

Authors:  T BITTER; H M MUIR
Journal:  Anal Biochem       Date:  1962-10       Impact factor: 3.365

2.  Aliphatic ammonium salts in the assay of acidic polysaccharides from tissues.

Authors:  J E SCOTT
Journal:  Methods Biochem Anal       Date:  1960

3.  A modified colorimetric method for the estimation of N-acetylamino sugars.

Authors:  J L REISSIG; J L STORMINGER; L F LELOIR
Journal:  J Biol Chem       Date:  1955-12       Impact factor: 5.157

4.  The influence of the intrapolymer environment on periodate oxidation of uronic acids in polyuronides and glycosaminoglycuronans.

Authors:  J E Scott; M J Tigwell
Journal:  Biochem Soc Trans       Date:  1975       Impact factor: 5.407

5.  Periodate oxidation and the shapes of glycosaminoglycuronans in solution.

Authors:  J E Scott; M J Tigwell
Journal:  Biochem J       Date:  1978-07-01       Impact factor: 3.857

6.  Preparation and circular dichroism analysis of sodium hyaluronate oligosaccharides and chondroitin.

Authors:  M K Cowman; E A Balazs; C W Bergmann; K Meyer
Journal:  Biochemistry       Date:  1981-03-03       Impact factor: 3.162

7.  1H nuclear-magnetic-resonance spectra of the methyl group of the acetamido moiety and the structure of acid glycosaminoglycans in solution.

Authors:  J E Scott; F Heatley
Journal:  Biochem J       Date:  1979-08-01       Impact factor: 3.857

8.  P.m.r. spectra and conformation of the pyranose amino sugars, 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-alpha-D-galactopyranose, and 2-acetamido-2-deoxy-beta-D-mannopyranose.

Authors:  T J Schamper
Journal:  Carbohydr Res       Date:  1974-08       Impact factor: 2.104

9.  Proteoglycan-collagen arrangements in developing rat tail tendon. An electron microscopical and biochemical investigation.

Authors:  J E Scott; C R Orford; E W Hughes
Journal:  Biochem J       Date:  1981-06-01       Impact factor: 3.857
  9 in total
  7 in total

1.  1H-NMR study of GM2 ganglioside: evidence that an interresidue amide-carboxyl hydrogen bond contributes to stabilization of a preferred conformation.

Authors:  S B Levery
Journal:  Glycoconj J       Date:  1991-12       Impact factor: 2.916

2.  Hyaluronan: the absence of amide-carboxylate hydrogen bonds and the chain conformation in aqueous solution are incompatible with stable secondary and tertiary structure models.

Authors:  Charles D Blundell; Paul L Deangelis; Andrew Almond
Journal:  Biochem J       Date:  2006-06-15       Impact factor: 3.857

3.  The molecular basis of the solution properties of hyaluronan investigated by confocal fluorescence recovery after photobleaching.

Authors:  P Gribbon; B C Heng; T E Hardingham
Journal:  Biophys J       Date:  1999-10       Impact factor: 4.033

4.  Secondary structure of hyaluronate in solution. A 1H-n.m.r. investigation at 300 and 500 MHz in [2H6]dimethyl sulphoxide solution.

Authors:  J E Scott; F Heatley; W E Hull
Journal:  Biochem J       Date:  1984-05-15       Impact factor: 3.857

5.  Detection of secondary structure in glycosaminoglycans via the H n.m.r. signal of the acetamido NH group.

Authors:  J E Scott; F Heatley
Journal:  Biochem J       Date:  1982-10-01       Impact factor: 3.857

6.  UDP-glucose Dehydrogenase: The First-step Oxidation Is an NAD+-dependent Bimolecular Nucleophilic Substitution Reaction (SN2).

Authors:  Jun Chen; Yang Yu; Jiaojiao Gao; Shulin Yang
Journal:  Int J Biol Sci       Date:  2019-01-01       Impact factor: 6.580

7.  Constructing 3-Dimensional Atomic-Resolution Models of Nonsulfated Glycosaminoglycans with Arbitrary Lengths Using Conformations from Molecular Dynamics.

Authors:  Elizabeth K Whitmore; Devon Martin; Olgun Guvench
Journal:  Int J Mol Sci       Date:  2020-10-18       Impact factor: 5.923
  7 in total

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