Literature DB >> 6802533

Leucocyte migration inhibition response to tissue antigens in asymptomatic individuals infected with Trypanosoma cruzi.

J M Peralta, K Gill, M F Cordeiro Lima, J R Coura.   

Abstract

The direct leucocyte migration inhibition test was used to study 31 asymptomatic humans chronically infected with Trypanosoma cruzi and 23 normal uninfected controls. The antigenic preparations used were made from mouse and guinea-pig heart, skeletal muscle, kidney, liver and brain. Positive responses were found in the parasite-infected individuals to kidney, liver and brain antigen but not to antigen prepared from heart of skeletal muscle tissue. No correlation was found between T. cruzi antibody titres and migration index values to these various antigens. On the other hand, a positive correlation was only noted between the titres of tissue-reacting immunoglobulins and the migration indices induced by brain antigens: when titres of tissue-reacting immunoglobulins were elevated, less leucocyte migration inhibition was detected.

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Year:  1981        PMID： 6802533      PMCID： PMC1537406     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  14 in total

1.  Circulating antibodies to peripheral nerve in American trypanosomiasis (Chagas' disease).

Authors:  E L Khoury; V Ritacco; P M Cossio; R P Laguens; A Szarfman; C Diez; R M Arana
Journal:  Clin Exp Immunol       Date:  1979-04       Impact factor: 4.330

2.  In vitro cellular immunity in Chagas' disease.

Authors:  M A Toledo Barros; V Amato Neto; E Mendes; I Mota
Journal:  Clin Exp Immunol       Date:  1979-11       Impact factor: 4.330

3.  [Clinical and radiological aspects of aperistalsis of the esophagus].

Authors:  J de REZENDE; K M LAUAR; A de OLIVEIRA
Journal:  Rev Bras Gastroenterol       Date:  1960 Sep-Dec

4.  Chagasic cardiopathy. Demonstration of a serum gamma globulin factor which reacts with endocardium and vascular structures.

Authors:  P M Cossio; C Diez; A Szarfman; E Kreutzer; B Candiolo; R M Arana
Journal:  Circulation       Date:  1974-01       Impact factor: 29.690

5.  Migration enhancement factor: a new lymphokine.

Authors:  R H Weisbart; R Bluestone; L S Goldberg; C M Pearson
Journal:  Proc Natl Acad Sci U S A       Date:  1974-03       Impact factor: 11.205

6.  Leucocyte migration inhibition by heart extract and liver mitochondria in patients with myocardial infarction.

Authors:  J Wartenberg; J Brostoff
Journal:  Br Heart J       Date:  1973-08

7.  Immunologic and immunopathologic studies in congenital Chagas' disease.

Authors:  A Szarfman; P M Cossio; R M Arana; J Urman; E Kreutzer; R P Laguens; A Segal; L Coarasa
Journal:  Clin Immunol Immunopathol       Date:  1975-11

8.  Leukocyte migration inhibition test with heart antigens in American trypanosomiasis.

Authors:  M T de la Vega; G Damilano; C Diez
Journal:  J Parasitol       Date:  1976-02       Impact factor: 1.276

9.  Tissue-reacting antibodies (EVI antibodies) in nifurtimox-treated patients with Chagas's disease.

Authors:  G A Schmuñis; P M Cossio; A Szarfman; L Coarasa; R M Arana
Journal:  J Infect Dis       Date:  1978-09       Impact factor: 5.226

10.  Products of activated lymphocytes: leukocyte inhibitory factor (LIF) distinct from migration inhibitory factor (MIF).

Authors:  R E Rocklin
Journal:  J Immunol       Date:  1974-04       Impact factor: 5.422
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