Literature DB >> 6798606

A comparison of plasma and serum levels of two tricyclic antidepressants: imipramine and desipramine.

J J Saady, V L Bloom, N Narasimhachari, S C Goldberg, R O Friedel.   

Abstract

This study was performed to determine the difference, if any, between serum and plasma levels of the tricyclic antidepressant drugs imipramine and desipramine. Serum and plasma samples were drawn simultaneously from patients taking either of these drugs. Statistical analysis indicated no difference in the drug levels; that is, serum and plasma levels were identical.

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Year:  1981        PMID： 6798606     DOI： 10.1007/BF00432182

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  7 in total

1.  Correlation between plasma levels of nortriptyline and clinical effects.

Authors:  P Kragh-Sørensen
Journal:  Commun Psychopharmacol       Date:  1978

2.  Amitriptyline plasma levels and clinical response in primary depression: II.

Authors:  D J Kupfer; I Hanin; D Spiker; J Neil; P Coble; T Grau; C Nevar
Journal:  Commun Psychopharmacol       Date:  1978

3.  Studies on plasma level/effect relationships in imipramine therapy.

Authors:  J M Perel; R L Stiller; A H Glassman
Journal:  Commun Psychopharmacol       Date:  1978

4.  The clinical impact of blood collection methods on tricyclic antidepressants as measured by GC/MS-SIM.

Authors:  R C Veith; V A Raisys; C Perera
Journal:  Commun Psychopharmacol       Date:  1978

5.  Plasma concentrations of protriptyline and clinical effects in depressed women.

Authors:  S F Whyte; A J Macdonald; G J Naylor; J P Moody
Journal:  Br J Psychiatry       Date:  1976-04       Impact factor: 9.319

6.  Prediction of steady-state imipramine and desmethylimipramine plasma concentrations from single-dose data.

Authors:  D J Brunswick; J D Amsterdam; J Mendels; S L Stern
Journal:  Clin Pharmacol Ther       Date:  1979-05       Impact factor: 6.875

7.  Analysis of tricyclic antidepressants in human plasma by GLC--chemical-ionization mass spectrometry with selected ion monitoring.

Authors:  R G Jenkins; R O Friedel
Journal:  J Pharm Sci       Date:  1978-01       Impact factor: 3.534
  7 in total

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