Literature DB >> 6796770

S-Adenosylhomocysteine hydrolase activity in a lymphoblastoid cell line from a patient with adenosine deaminase dificiency disease.

S Tsuchiya, S Nakae, T Konno, K Tada.   

Abstract

S-Adenosylhomocysteine (S-AdoHcy) hydrolase activity in a lymphoblastoid cell line from a patient with adenosine deaminase deficiency disease (ADA(-)LCL) was found to be approximately 60% of that in ADA (+)lymphoblastoid cell lines. S-AdoHcy hydrolase of ADA(-)LCL was more sensitive to inhibition by 2'-deoxyadenosine as compared with that of ADA(+)LCL. The inhibitory effect of 2'-deoxyadenosine was evident in cell growth and immunoglobulin production of lymphoblastoid cell lines.

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Year:  1981        PMID： 6796770     DOI： 10.1007/BF02263651

Source DB:  PubMed          Journal:  J Inherit Metab Dis        ISSN： 0141-8955            Impact factor:   4.982


  14 in total

1.  A lymphoblastoid cell line from an adenosine deaminase deficient patient established by Epstein-Barr virus.

Authors:  S Tsuchiya; K Narisawa; T Konno; K Tada
Journal:  Tohoku J Exp Med       Date:  1979-10       Impact factor: 1.848

2.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

3.  Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease.

Authors:  B Ullman; L J Gudas; A Cohen; D W Martin
Journal:  Cell       Date:  1978-06       Impact factor: 41.582

4.  Differential inhibition of adenosine deaminase deficient peripheral blood lymphocytes and lymphoid line cells by deoxyadenosine and adenosine.

Authors:  R Hirschhorn; S Bajaj; W Borkowsky; A Kowalski; R Hong; A Rubinstein; P Papageorgiou
Journal:  Cell Immunol       Date:  1979-02       Impact factor: 4.868

5.  Inhibition of methylation by adenosine in adenosine deaminase-inhibited, phytohemagglutinin-stimulated human lymphocytes.

Authors:  J M Johnston; N M Kredich
Journal:  J Immunol       Date:  1979-07       Impact factor: 5.422

6.  Apparent suicide inactivation of human lymphoblast S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine and adenine arabinoside. A basis for direct toxic effects of analogs of adenosine.

Authors:  M S Hershfield
Journal:  J Biol Chem       Date:  1979-01-10       Impact factor: 5.157

7.  The effect of nucleosides and deoxycoformycin on adenosine and deoxyadenosine inhibition of human lymphocyte activation.

Authors:  J Uberti; J J Lightbody; R M Johnson
Journal:  J Immunol       Date:  1979-07       Impact factor: 5.422

8.  Epstein-Barr virus-induced lymphoblastoid cell lines from patients with primary immunodeficiency diseases.

Authors:  S Tsuchiya; T Konno; K Tada; Y Ono
Journal:  Scand J Immunol       Date:  1980       Impact factor: 3.487

9.  Selective toxicity of purine deoxynucleosides for human lymphocyte growth and function.

Authors:  E W Gelfand; J J Lee; H M Dosch
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

10.  In vivo inactivation of erythrocyte S-adenosylhomocysteine hydrolase by 2'-deoxyadenosine in adenosine deaminase-deficient patients.

Authors:  M S Hershfield; N M Kredich; D R Ownby; H Ownby; R Buckley
Journal:  J Clin Invest       Date:  1979-04       Impact factor: 14.808
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  1 in total

Review 1.  Transmethylation in immunity and autoimmunity.

Authors:  Brian R Lawson; Theodoros Eleftheriadis; Virginie Tardif; Rosana Gonzalez-Quintial; Roberto Baccala; Dwight H Kono; Argyrios N Theofilopoulos
Journal:  Clin Immunol       Date:  2011-12-24       Impact factor: 3.969
  1 in total

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