| Literature DB >> 6796693 |
H R Ingham, P R Sisson, R L Middleton, H K Narang, A A Codd, J B Selkon.
Abstract
Phagocytosis and intracellular killing of several facultative anaerobes were observed in aerobic and anaerobic conditions. The presence of anaerobes affected these processes. Bacteroides asaccharolyticus and B. fragilis were killed by phagocytes only at bacterial concentrations less than 1 x 10(7) cfu/ml; at higher concentrations of the anaerobes, killing of B. fragilis and concomitant facultative anaerobes was inhibited. This effect appeared to be due to an interaction, in appropriate reducing conditions, between anaerobe and serum, which allowed engulfment of organisms by phagocytes but markedly impaired intracellular killing.Entities:
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Year: 1981 PMID： 6796693 DOI： 10.1099/00222615-14-4-391
Source DB: PubMed Journal: J Med Microbiol ISSN： 0022-2615 Impact factor: 2.472