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Literature DB >> 67966

Zinc biochemistry in normal and neoplastic growth processes.

Abstract

Zinc is essential for the growth of all species. Growth arrest results from its deficiency and presumably reflects important roles for this metal at critical points of metabolism. Studies of zinc metalloenzymes show that zinc serves as a coenzyme to more than 80 enzymes, among which are the reverse transcriptases which cause leukemia in many species. Its role in nucleic acid metabolism is emphasized.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1977 PMID： 67966 DOI： 10.1007/BF01946521

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

9 in total

1. Biochemistry, physiology and pathology of zinc.

Authors: B L VALLEE
Journal: Physiol Rev Date: 1959-07 Impact factor: 37.312

2. Nucleic acids and metals. III. Changes in nucleic acid, protein, and metal content as a consequence of zinc deficiency in Euglena gracilis.

Authors: W E WACKER
Journal: Biochemistry Date: 1962-09 Impact factor: 3.162

3. Euglena gracilis, A Test Organism for Study of Zinc.

Authors: C A Price; B L Vallee
Journal: Plant Physiol Date: 1962-05 Impact factor: 8.340

Review 4. RNA-directed DNA synthesis and RNA tumor viruses.

Authors: H M Temin; D Baltimore
Journal: Adv Virus Res Date: 1972 Impact factor: 9.937

5. Zinc reverse transcriptases from mammalian RNA type C viruses.

Authors: D S Auld; H Kawaguchi; D M Livingston; B L Vallee
Journal: Biochem Biophys Res Commun Date: 1975-01-20 Impact factor: 3.575

6. Zinc in DNA polymerases.

Authors: J P Slater; A S Mildvan; L A Loeb
Journal: Biochem Biophys Res Commun Date: 1971-07-02 Impact factor: 3.575

7. The presence and possible role of zinc in RNA polymerase obtained from Escherichia coli.

Authors: M C Scrutton; C W Wu; D A Goldthwait
Journal: Proc Natl Acad Sci U S A Date: 1971-10 Impact factor: 11.205

8. RNA-dependent DNA polymerase (reverse transcriptase) from avian myeloblastosis virus: a zinc metalloenzyme.

Authors: D S Auld; H Kawaguchi; D M Livingston; B L Vallee
Journal: Proc Natl Acad Sci U S A Date: 1974-05 Impact factor: 11.205

9. Role of zinc in cell division of Euglena gracilis.

Authors: K H Falchuk; D W Fawcett; B L Vallee
Journal: J Cell Sci Date: 1975-01 Impact factor: 5.285

9 in total

8 in total

Zinc biochemistry in normal and neoplastic growth processes.

1. Biochemistry, physiology and pathology of zinc.

2. Nucleic acids and metals. III. Changes in nucleic acid, protein, and metal content as a consequence of zinc deficiency in Euglena gracilis.

3. Euglena gracilis, A Test Organism for Study of Zinc.

Review 4. RNA-directed DNA synthesis and RNA tumor viruses.

5. Zinc reverse transcriptases from mammalian RNA type C viruses.

6. Zinc in DNA polymerases.

7. The presence and possible role of zinc in RNA polymerase obtained from Escherichia coli.

8. RNA-dependent DNA polymerase (reverse transcriptase) from avian myeloblastosis virus: a zinc metalloenzyme.

9. Role of zinc in cell division of Euglena gracilis.

Review 1. Current status of zinc in health and disease states.

2. Serum and tissue zinc concentrations in patients with endoscopic esophagitis.

3. Zinc fingers, zinc clusters, and zinc twists in DNA-binding protein domains.

4. Zinc levels in zinc-stabilized insulin are inhibitory to the growth of cells in vitro.

5. Zinc-binding protein in the livers of neonatal, normal and partially hepatectomized rats.

6. Zinc rapidly induces a metal response element-binding factor.

7. Purification, characterization and anti-aging capacity of mycelia zinc polysaccharide by Lentinus edodes SD-08.

8. Vitamin A, zinc and lung cancer.