Literature DB >> 6796342

Intrathecal chemotherapy for leptomeningeal dissemination of medulloblastoma.

M S Edwards, V A Levin, M L Seager, C B Wilson.   

Abstract

Cerebrospinal fluid dissemination of medulloblastoma occurs despite adequate systemic chemotherapy, and unless it is present at the time of initial diagnosis, occurs late in the course of the disease. Intrathecal chemotherapy with an implanted Ommaya reservoir can produce short-term benefit. We report here our protocol for and the results of intrathecal chemotherapy for leptomeningeal dissemination of medulloblastoma.

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Year:  1981        PMID： 6796342     DOI： 10.1159/000120013

Source DB:  PubMed          Journal:  Childs Brain        ISSN： 0302-2803


  12 in total

1.  Lipid association increases the potency against primary medulloblastoma cells and systemic exposure of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) in rats.

Authors:  C Bethune; A Blum; J R Geyer; J R Silber; R J Ho
Journal:  Pharm Res       Date:  1999-06       Impact factor: 4.200

2.  Prospective randomized cooperative medulloblastoma trial (MED 84) of the International Society of Paediatric Oncology (SIOP) and of the (German) Society of Paediatric Oncology (GPO).

Authors:  M K Neidhardt; C C Bailey
Journal:  Childs Nerv Syst       Date:  1987       Impact factor: 1.475

Review 3.  The chemotherapy of posterior fossa tumors in childhood.

Authors:  H S Friedman; W J Oakes
Journal:  J Neurooncol       Date:  1987       Impact factor: 4.130

4.  Intrathecal chemotherapy with MX2 for treating glioma dissemination in vivo.

Authors:  S Mizumatsu; K Matsumoto; Y Ono; T Tamiya; T Furuta; T Ohmoto
Journal:  J Neurooncol       Date:  2000-08       Impact factor: 4.130

5.  Neurotoxicity and pharmacokinetics of ventriculolumbar perfusion of methyl 6-[3-(2-chloroethyl)-3-nitrosoureido]-6-deoxy-alpha-D-glucopyranoside (MCNU) in dogs.

Authors:  M Kochi; S Takaki; J Kuratsu; H Seto; I Kitamura; Y Ushio
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

6.  MRI of subarachnoid dissemination of medulloblastoma.

Authors:  M Kochi; Y Mihara; A Takada; C Yatomi; M Morioka; S Yamashiro; S Yano; J Kuratsu; S Uemura; Y Ushio
Journal:  Neuroradiology       Date:  1991       Impact factor: 2.804

7.  An adoptive immunotherapy of patients with medulloblastoma by lymphokine-activated killer cells (LAK).

Authors:  Y Okamoto; K Shimizu; K Tamura; Y Miyao; M Yamada; Y Matsui; N Tsuda; H Takimoto; T Hayakawa; H Mogami
Journal:  Acta Neurochir (Wien)       Date:  1988       Impact factor: 2.216

8.  Direct delivery of platinum-based antineoplastics to the central nervous system: a toxicity and ultrastructural study.

Authors:  A Olivi; M Gilbert; K L Duncan; B Corden; D Lenartz; H Brem
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

9.  Ventriculolumber perfusion of 3-[(4-amino-2-methyl-5-pyrimidinyl)-methyl]-1-(2-chloroethyl-1-nitrosou rea hydrochloride for subarachnoid dissemination of gliomas.

Authors:  Y Ushio; M Kochi; I Kitamura; J Kuratsu
Journal:  J Neurooncol       Date:  1998 Jun-Jul       Impact factor: 4.130

10.  Cerebellar medulloblastomas in adults.

Authors:  F Ildan; E Cetinalp; H Bağdatoğlu; B Boyar; S Haciyakupoğlu; A Karadayi
Journal:  Neurosurg Rev       Date:  1994       Impact factor: 3.042
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