| Literature DB >> 6795661 |
Abstract
Amphetamine anorexia in rats was potentiated by acute pretreatment with the tricyclic antidepressant desmethylimipramine (DMI), but was not significantly different from controls following chronic DMI pretreatment. During withdrawal from DMI, amphetamine anorexia was attenuated after 2 weeks or 2 months pretreatment, but not after 1 week of treatment. The locomotor stimulant and stereotypy inducing effects of amphetamine were slightly enhanced during withdrawal from chronic DMI. The results are discussed in relation to known neurochemical actions of DMI.Entities:
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Year: 1981 PMID: 6795661 DOI: 10.1007/BF00433502
Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN: 0033-3158 Impact factor: 4.530