Literature DB >> 6795315

Intravenous nitroglycerin for the treatment of chronic cerebral vasoconstriction in the primate.

J G Frazee, S L Giannotta, W E Stern.   

Abstract

A primate model of chronic cerebral vasoconstriction is presented which closely approximates the human experience following subarachnoid hemorrhage. Treatment of the vasoconstriction with intravenous nitroglycerin produces a modest, but statistically significant, increase in the size of the most constricted vessels (11%, p less than 0.02) when compared with a control infusion of normal saline. The significance of these experiments is discussed.

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Year:  1981        PMID： 6795315     DOI： 10.3171/jns.1981.55.6.0865

Source DB:  PubMed          Journal:  J Neurosurg        ISSN： 0022-3085            Impact factor:   5.115


  4 in total

1.  Effects of intravenous nitroglycerin combined with dopamine on intracranial pressure and cerebral arteriovenous oxygen difference in patients with acute subarachnoid haemorrhage.

Authors:  H Iwanaga; K Okuchi; N Koshimae; K Goda; M Imanishi; H Tokunaga; H Aoki; E Boku; T Sakaki
Journal:  Acta Neurochir (Wien)       Date:  1995       Impact factor: 2.216

2.  Timing of ICAM-I Expression in a Canine Model of Post-Haemorrhagic Cerebral Vasospasm.

Authors:  T Abruzzo; G G Shengelaia; H J Cloft; G Thaxton; P Dudley; F Tong; J E Dion
Journal:  Interv Neuroradiol       Date:  2001-05-15       Impact factor: 1.610

Review 3.  Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH.

Authors:  R M Pluta
Journal:  Acta Neurochir Suppl       Date:  2008

4.  Nitric oxide in cerebral vasospasm: theories, measurement, and treatment.

Authors:  Michael Siuta; Scott L Zuckerman; J Mocco
Journal:  Neurol Res Int       Date:  2013-06-25
  4 in total

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