Literature DB >> 6795056

Antifertility effects of clonidine in laying hens.

R M Weppelman, R L Tolman, A A Van Iderstine, L Peterson, G Olson.   

Abstract

Clonidine was anovulatory and markedly antigonadal in laying hens when infused for 1 week from minipump implants at daily rates of 1.08 mg per hen or greater. The ovaries of hens treated with clonidine responded to FSH injections which suggests that the antigonadal effect of clonidine resulted from a reduction in the output of gonadotropin by the pituitary. These data suggest that alpha 2 receptors may be important in regulating avian fertility.

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Year:  1981        PMID: 6795056     DOI: 10.1007/BF01971800

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  15 in total

1.  Effect of dibenamine on progesterone-induced and spontaneous ovulation in the hen.

Authors:  A VAN TIENHOVEN; A V NALBANDOV; H W NORTON
Journal:  Endocrinology       Date:  1954-06       Impact factor: 4.736

2.  Quantitative structure-activity relationships in centrally acting imidazolidines structurally related to clonidine.

Authors:  P B Timmermans; P A van Zwieten
Journal:  J Med Chem       Date:  1977-12       Impact factor: 7.446

Review 3.  Subclassification of alpha-adrenergic receptors by direct binding studies.

Authors:  C L Wood; C D Arnett; W R Clarke; B S Tsai; R J Lefkowitz
Journal:  Biochem Pharmacol       Date:  1979-04-15       Impact factor: 5.858

4.  The effect of antiadrenergic drugs on ovulation in hens.

Authors:  L W Kao; A V Nalbandov
Journal:  Endocrinology       Date:  1972-05       Impact factor: 4.736

5.  Direct effect on the ovary of the adrenergic blocking drug dibenzyline.

Authors:  G Ferrando; A V Nalbandov
Journal:  Endocrinology       Date:  1969-07       Impact factor: 4.736

6.  Antifertility effects of dithiocarbamates in laying hens.

Authors:  R M Weppelman; R A Long; A Van Iderstine; J E Taylor; R L Tolman; L Peterson; G Olson
Journal:  Biol Reprod       Date:  1980-08       Impact factor: 4.285

7.  [3H]Para-amino-clonidine: a novel ligand which binds with high affinity to alpha-adrenergic receptors.

Authors:  B R Rouot; S H Snyder
Journal:  Life Sci       Date:  1979-08-27       Impact factor: 5.037

8.  The effect of reserpine on plasma LH concentrations in intact and gonadectomised domestic fowl.

Authors:  P J Sharp
Journal:  Br Poult Sci       Date:  1975-01       Impact factor: 2.095

9.  Effect of clonidine on growth hormone, prolactin, luteinizing hormone, follicle-stimulating hormone, and thyroid-stimulating hormone in the serum of normal men.

Authors:  S Lal; G Tolis; S B Martin; G M Brown; H Guyda
Journal:  J Clin Endocrinol Metab       Date:  1975-11       Impact factor: 5.958

10.  Antagonism by clonidine of neuronal depressant responses to adenosine, adenosine-5'-monophosphate and adenosine triphosphate.

Authors:  T W Stone; D A Taylor
Journal:  Br J Pharmacol       Date:  1978-11       Impact factor: 8.739

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