Literature DB >> 679503

The effect of propranolol on thyroid hormones and oxygen consumption in thyrotoxicosis.

J Saunders, S E Hall, A Crowther, P H Sönksen.   

Abstract

The possibility that propranolol may exert its beneficial actions in thyrotoxicosis by an effect on thyroid hormone concentrations has been investigated by measuring these and oxygen consumption in a group of thyrotoxic patients before and after treatment with propranolol. Following treatment a significant fall in plasma T3 concentration and oxygen consumption occurred and a direct correlation was found between these two variables. Propranolol may, therefore, exert some of its beneficial effects in thyrotoxicosis by an action on T3 metabolism.

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Year:  1978        PMID： 679503     DOI： 10.1111/j.1365-2265.1978.tb03573.x

Source DB:  PubMed          Journal:  Clin Endocrinol (Oxf)        ISSN： 0300-0664            Impact factor:   3.478


  7 in total

1.  Oxygen consumption in patients with hyperthyroidism before and after treatment with beta-blockade versus thyrostatic treatment: a prospective randomized study.

Authors:  S Jansson; K Lie-Karlsen; O Stenqvist; U Körner; K Lundholm; L E Tisell
Journal:  Ann Surg       Date:  2001-01       Impact factor: 12.969

2.  A study of long acting propranolol in the early management of hyperthyroidism.

Authors:  G R Jones; J H Lazarus; D Wynford-Thomas
Journal:  Br J Clin Pharmacol       Date:  1981-12       Impact factor: 4.335

3.  Nadolol in thyrotoxicosis.

Authors:  N R Peden; T E Isles; I H Stevenson; J Crooks
Journal:  Br J Clin Pharmacol       Date:  1982-06       Impact factor: 4.335

4.  D-propranolol and DL-propranolol both decrease conversion of L-thyroxine to L-triiodothyronine.

Authors:  P Heyma; R G Larkins; L Higginbotham; K W Ng
Journal:  Br Med J       Date:  1980-07-05

Review 5.  Use of beta-adrenoceptor blocking drugs in hyperthyroidism.

Authors:  J Feely; N Peden
Journal:  Drugs       Date:  1984-05       Impact factor: 9.546

6.  Effect of propranolol on thyroid homeostasis of healthy volunteers.

Authors:  M R Wilkins; J A Franklyn; K L Woods; M J Kendall
Journal:  Postgrad Med J       Date:  1985-05       Impact factor: 2.401

7.  Comparison of propranolol and metoprolol in the management of hyperthyroidism.

Authors:  L E Murchison; J How; P D Bewsher
Journal:  Br J Clin Pharmacol       Date:  1979-12       Impact factor: 4.335
  7 in total

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