Literature DB >> 6794822

DR antigens and rheumatoid arthritis: a study of two populations.

J C Woodrow, F E Nichol, G Zaphiropoulos.   

Abstract

Thr prevalence of HLA-DR antigens was determined in a group of white patients with rheumatoid arthritis, similar patients originating from the Indian subcontinent, and corresponding controls. Rheumatoid arthritis was found to be highly associated with DR4 in the white patients but with DR1 in the Indian patients. These results raise the possibility that the DR antigens themselves do not play a part in increasing susceptibility to rheumatoid arthritis, but the locus for increased susceptibility is probably closely linked to the DR locus.

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Year:  1981        PMID: 6794822      PMCID: PMC1507681          DOI: 10.1136/bmj.283.6302.1287

Source DB:  PubMed          Journal:  Br Med J (Clin Res Ed)        ISSN: 0267-0623


  8 in total

1.  The estimation and significance of the logarithm of a ratio of frequencies.

Authors:  J B HALDANE
Journal:  Ann Hum Genet       Date:  1956-05       Impact factor: 1.670

2.  Structural studies of murine I-E and human DR antigens.

Authors:  J Silver; L E Walker; R A Reisfeld; M A Pellegrino; S Ferrone
Journal:  Mol Immunol       Date:  1979-01       Impact factor: 4.407

3.  Simultaneous detection of two cell populations by two-colour fluorescence and application to the recognition of B-cell determinants.

Authors:  J J van Rood; A van Leeuwen; J S Ploem
Journal:  Nature       Date:  1976-08-26       Impact factor: 49.962

4.  [Association of HLA-DR and adult rheumatoid polyarthritis in southern France].

Authors:  P Mercier; R Dallest; H Roux
Journal:  Nouv Presse Med       Date:  1980-03-22

5.  Rheumatoid arthritis and B lymphocyte alloantigen HLA-DRw4.

Authors:  O Scherak; J S Smolen; W R Mayr
Journal:  J Rheumatol       Date:  1980 Jan-Feb       Impact factor: 4.666

6.  Association of the B-cell alloantigen DRw4 with rheumatoid arthritis.

Authors:  P Stastny
Journal:  N Engl J Med       Date:  1978-04-20       Impact factor: 91.245

7.  Genetic basis of rheumatoid disease: HLA antigens, disease manifestations, and toxic reactions to drugs.

Authors:  G S Panayi; P Wooley; J R Batchelor
Journal:  Br Med J       Date:  1978-11-11

8.  Association of HLA-DRw4 with rheumatoid arthritis in black and white patients.

Authors:  R W Karr; G E Rodey; T Lee; B D Schwartz
Journal:  Arthritis Rheum       Date:  1980-11
  8 in total
  29 in total

Review 1.  The immunogenetics of rheumatoid arthritis.

Authors:  B P Wordsworth; J I Bell
Journal:  Springer Semin Immunopathol       Date:  1992

Review 2.  Polygenic susceptibility in rheumatoid arthritis.

Authors:  P Wordsworth; J Bell
Journal:  Ann Rheum Dis       Date:  1991-06       Impact factor: 19.103

3.  HLA-DR4-DQw8, but not DR4-DQw7 haplotypes occur in Indian patients with rheumatoid arthritis.

Authors:  V Taneja; N K Mehra; A N Chandershekaran; R K Ahuja; Y N Singh; A N Malaviya
Journal:  Rheumatol Int       Date:  1992       Impact factor: 2.631

4.  Polyclonal antibody directed against human RANTES ameliorates disease in the Lewis rat adjuvant-induced arthritis model.

Authors:  D A Barnes; J Tse; M Kaufhold; M Owen; J Hesselgesser; R Strieter; R Horuk; H D Perez
Journal:  J Clin Invest       Date:  1998-06-15       Impact factor: 14.808

5.  HLA haplotype sharing by siblings with rheumatoid arthritis: evidence for genetic heterogeneity.

Authors:  D M Grennan; P A Sanders; P A Dyer; R Harris
Journal:  Ann Rheum Dis       Date:  1986-02       Impact factor: 19.103

6.  Strong association of rheumatoid arthritis with the presence of a polymorphic Ia epitope defined by a monoclonal antibody: comparison with the allodeterminant DR4.

Authors:  S H Lee; P K Gregersen; H H Shen; A Nunez-Roldan; J Silver; R J Winchester
Journal:  Rheumatol Int       Date:  1984       Impact factor: 2.631

Review 7.  The molecular basis of susceptibility to rheumatoid arthritis: the conformational equivalence hypothesis.

Authors:  R J Winchester; P K Gregersen
Journal:  Springer Semin Immunopathol       Date:  1988

8.  Anti-neutrophil cytoplasm antibodies (ANCA) in rheumatoid arthritis: relationship to HLA-DR phenotypes, rheumatoid factor, anti-nuclear antibodies and disease severity.

Authors:  E Röther; D Metzger; B Lang; I Melchers; H H Peter
Journal:  Rheumatol Int       Date:  1994       Impact factor: 2.631

9.  Weak association between HLA-DR4 and rheumatoid arthritis in Chilean patients.

Authors:  L Massardo; S Jacobelli; L Rodríguez; S Rivero; A González; R Marchetti
Journal:  Ann Rheum Dis       Date:  1990-05       Impact factor: 19.103

10.  HLA class II and T-cell receptor beta chain polymorphisms in Belgian patients with rheumatoid arthritis: no evidence for disease association with the TCRBC2, TCRBV8 and TCRBV11 polymorphisms.

Authors:  C Vandevyver; X X Gu; P Geusens; M Spaepen; L Philippaerts; J J Cassiman; J Raus
Journal:  Ann Rheum Dis       Date:  1994-09       Impact factor: 19.103

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