Literature DB >> 6793567

Suppression of calcium-induced removal of the Z-line by a thiol-protease inhibitor, E-64-c.

S Ishiura, I Nonaka, H Sugita.   

Abstract

A new thiol-protease inhibitor, E-64-c (N-[N-(L-3-carboxyoxirane-2-carbonyl)-L-leucyl]-isoamylamine), specifically suppressed the disappearance of the Z-line terminal by calcium in rat soleus muscle. This results suggests that calcium-activated neutral protease (CANP) may be involved in such calcium-mediated degeneration of myofilaments.

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Year:  1981        PMID： 6793567

Source DB:  PubMed          Journal:  J Biochem        ISSN： 0021-924X            Impact factor:   3.387


  6 in total

1.  Characterization of ultrastructural and contractile activation properties of crustacean (Cherax destructor) muscle fibres during claw regeneration and moulting.

Authors:  J M West; D C Humphris; D G Stephenson
Journal:  J Muscle Res Cell Motil       Date:  1995-06       Impact factor: 2.698

Review 2.  Structure and physiological function of calpains.

Authors:  H Sorimachi; S Ishiura; K Suzuki
Journal:  Biochem J       Date:  1997-12-15       Impact factor: 3.857

3.  Therapeutic trial with protease inhibitor (leupeptin) in chicken muscular dystrophy. A histologic and histochemical study.

Authors:  I Nonaka; S Ishiura; A Takagi; H Sugita
Journal:  Acta Neuropathol       Date:  1982       Impact factor: 17.088

4.  Immediate and delayed effects of a brief period of calcium loading, induced by the calcium channel agonist Bayer K 8644, on the ultrastructure and sarcolemmal integrity of murine diaphragm in vitro.

Authors:  N J Bannister; S J Publicover
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

5.  Thiol protease-specific inhibitor E-64 arrests human epidermoid carcinoma A431 cells at mitotic metaphase.

Authors:  Y Shoji-Kasai; M Senshu; S Iwashita; K Imahori
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

6.  Interacting effects of Ca2+ and hypoxia in the induction of sarcolemmal damage in mouse diaphragm in vitro.

Authors:  N J Bannister; S J Publicover
Journal:  Acta Neuropathol       Date:  1995       Impact factor: 17.088
  6 in total

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