[Effects of muscular exercise on non-glucoregulatory hormones (T3, rT3, T4, TSH, prolactin, FSH, LH) in type I diabetics (author's transl)].

In the present investigation the influence of muscular exercise on non-glucoregulatory hormones (T3, rT3, T4, TSH, prolactin) was analyzed in non-ketotic, juvenile-onset type diabetics (JD) in relation of their metabolic control. The plasma hormonal concentrations were measured in 8 well-controlled JD, 8 moderately controlled JD and in 8 healthy subjects, before, during and after a 30 min. bicycle ergometer test of moderate work intensity. The exercise-induced rise in T4, and rT3 was similar in both groups of diabetics and did not significantly differ with that obtained in controls. A significant increase of T3-concentrations occurred only in the controls. Hormone levels of TSH, FSH and LH did not change significantly during exercise in all three groups, whereas prolactin showed a considerable increase (N. S.) in the well-controlled JD-patient group with low blood glucose concentrations. These findings demonstrate that muscular exercise leads to a similar effect on the behavior of T4, rT3, TSH, LH, and FSH concentrations, but not on T3 (no increase) and prolactin in non-ketotic, conventionally treated JD compared with healthy individuals.