| Literature DB >> 6792698 |
A Jung, C van Ouwenaller, A Chantraine, B Courvoisier.
Abstract
Two diphosphonates, EHDP (disodium etidronate, or ethane-hydroxy-diphosphonate) and Cl2MDP (disodium clodronate, or dichloromethylene-diphosphonate) were injected in various doses in 8 patients who had had one or more episodes of malignant hypercalcemia. All patients responded well to the drugs after a time lapse of 2-10 days. Tolerance of the drugs was excellent. EHDP, and especially Cl2MDP, are promising agents for the treatment of hypercalcemia and the inhibition of bone resorption in malignant disorders.Entities:
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Year: 1980 PMID: 6792698
Source DB: PubMed Journal: Schweiz Med Wochenschr ISSN: 0036-7672