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Literature DB >> 6791734

Oestrogen receptor proteins in malignant and fetal pancreas.

B Greenway, M J Iqbal, P J Johnson, R Williams.

Abstract

High levels of high-affinity oestrogen binding were detected in cytosolic and nuclear fractions of tumour tissue from six patients with pancreatic carcinoma. Similar binding was found in fetal but not in normal adult pancreas, making depression of fetal genes a possibility. Specific androgen binding was not detectable. These findings suggest that anti-oestrogen treatment may offer a new approach to the treatment of pancreatic carcinoma.

Entities: Disease Species

Mesh：

Substances：

Year: 1981 PMID： 6791734 PMCID： PMC1506873 DOI： 10.1136/bmj.283.6294.751

Source DB: PubMed Journal: Br Med J (Clin Res Ed) ISSN： 0267-0623

19 in total

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Journal: Steroids Date: 1974-06 Impact factor: 2.668

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47 in total

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6. Association of menstrual and reproductive factors with pancreatic cancer risk in women: findings of the Japan Collaborative Cohort Study for Evaluation of Cancer Risk.

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Authors: A Di Leo; C Messa; F Russo; G Misciagna; V Guerra; R Taveri; S Leo
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