Literature DB >> 6791661

Metabolism of dichlorobiphenyls by hepatic microsomal cytochrome P-450.

M W Kennedy, N K Carpentier, P P Dymerski, L S Kaminsky.   

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Year:  1981        PMID： 6791661     DOI： 10.1016/0006-2952(81)90129-5

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  10 in total

1.  Human Liver Microsomes Atropselectively Metabolize 2,2',3,4',6-Pentachlorobiphenyl (PCB 91) to a 1,2-Shift Product as the Major Metabolite.

Authors:  Eric Uwimana; Xueshu Li; Hans-Joachim Lehmler
Journal:  Environ Sci Technol       Date:  2018-04-27       Impact factor: 9.028

2.  Atropselective Oxidation of 2,2',3,3',4,6'-Hexachlorobiphenyl (PCB 132) to Hydroxylated Metabolites by Human Liver Microsomes and Its Implications for PCB 132 Neurotoxicity.

Authors:  Eric Uwimana; Brianna Cagle; Coby Yeung; Xueshu Li; Eric V Patterson; Jonathan A Doorn; Hans-Joachim Lehmler
Journal:  Toxicol Sci       Date:  2019-07-03       Impact factor: 4.849

3.  Metabolism of 3-Chlorobiphenyl (PCB 2) in a Human-Relevant Cell Line: Evidence of Dechlorinated Metabolites.

Authors:  Chun-Yun Zhang; Xueshu Li; Susanne Flor; Patricia Ruiz; Anneli Kruve; Gabriele Ludewig; Hans-Joachim Lehmler
Journal:  Environ Sci Technol       Date:  2022-08-22       Impact factor: 11.357

4.  Elimination of inhaled 3,3'-dichlorobiphenyl and the formation of the 4-hydroxylated metabolite.

Authors:  Xin Hu; Hans-Joachim Lehmler; Andrea Adamcakova-Dodd; Peter S Thorne
Journal:  Environ Sci Technol       Date:  2013-04-25       Impact factor: 9.028

5.  3,3'-Dichlorobiphenyl Is Metabolized to a Complex Mixture of Oxidative Metabolites, Including Novel Methoxylated Metabolites, by HepG2 Cells.

Authors:  Chun-Yun Zhang; Susanne Flor; Patricia Ruiz; Ram Dhakal; Xin Hu; Lynn M Teesch; Gabriele Ludewig; Hans-Joachim Lehmler
Journal:  Environ Sci Technol       Date:  2020-09-23       Impact factor: 9.028

6.  Hepatic metabolism affects the atropselective disposition of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice.

Authors:  Xianai Wu; Christopher Barnhart; Pamela J Lein; Hans-Joachim Lehmler
Journal:  Environ Sci Technol       Date:  2014-12-10       Impact factor: 9.028

7.  Microsomal Metabolism of Prochiral Polychlorinated Biphenyls Results in the Enantioselective Formation of Chiral Metabolites.

Authors:  Eric Uwimana; Anna Maiers; Xueshu Li; Hans-Joachim Lehmler
Journal:  Environ Sci Technol       Date:  2017-01-20       Impact factor: 9.028

8.  Semiquinone radicals from oxygenated polychlorinated biphenyls: electron paramagnetic resonance studies.

Authors:  Yang Song; Brett A Wagner; Hans-Joachim Lehmler; Garry R Buettner
Journal:  Chem Res Toxicol       Date:  2008-06-13       Impact factor: 3.739

9.  Characterization of the Metabolic Pathways of 4-Chlorobiphenyl (PCB3) in HepG2 Cells Using the Metabolite Profiles of Its Hydroxylated Metabolites.

Authors:  Chun-Yun Zhang; Susanne Flor; Patricia Ruiz; Gabriele Ludewig; Hans-Joachim Lehmler
Journal:  Environ Sci Technol       Date:  2021-06-14       Impact factor: 9.028

10.  5,5'-Dichloro-2,2'-dimeth-oxy-biphen-yl.

Authors:  Hans-Joachim Lehmler; Huimin Wu; Sean Parkin
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2013-04-05
  10 in total

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