Literature DB >> 6791207

Involvement of the amygdala in the effect of antidepressants on the passive avoidance deficit in bulbectomised rats.

D Garrigou, C L Broekkamp, K G Lloyd.   

Abstract

In the present study the role of the amygdala is demonstrated in the effect of antidepressant drugs on passive avoidance learning in bulbectomised rats. Imipramine, amitriptyline, or fluoxetine injected bilaterally (2 X 10 microgram) into the medial part of the amygdala improves passive avoidance learning by bulbectomised rats. Systemic pretreatment with metergoline attenuates the effect of local imipramine or fluoxetine injection. Microinjection of serotonin but not noradrenaline into the amygdala improves passive avoidance learning by bulbectomised rats. The relevance of the amygdala in the behavioral effects of antidepressants in animals is discussed.

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Year:  1981        PMID： 6791207     DOI： 10.1007/BF00431759

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  26 in total

1.  The differential projections of the olfactory bulb and accessory olfactory bulb in mammals.

Authors:  F Scalia; S S Winans
Journal:  J Comp Neurol       Date:  1975-05-01       Impact factor: 3.215

2.  A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine.

Authors:  D T Wong; J S Horng; F P Bymaster; K L Hauser; B B Molloy
Journal:  Life Sci       Date:  1974-08-01       Impact factor: 5.037

3.  Clonidine induced intrahypothalamic stimulation of eating in rats.

Authors:  C Broekkamp; J M van Rossum
Journal:  Psychopharmacologia       Date:  1972

4.  Evidence for inhibition by brain serotonin of mouse killing behaviour in rats.

Authors:  G Di Chiara; R Camba; P F Spano
Journal:  Nature       Date:  1971-09-24       Impact factor: 49.962

5.  Amygdaloid lesions and behavioral inhibition in the rat.

Authors:  L Pellegrino
Journal:  J Comp Physiol Psychol       Date:  1968-06

6.  Effects of psychotropic drugs injected into the limbic structures on mouse-killing behavior in the rat with olfactory bulb ablations.

Authors:  S Watanabe; M Inoue; S Ueki
Journal:  Jpn J Pharmacol       Date:  1979-06

7.  Olfactory projection systems, drugs and behaviour: a review.

Authors:  K D Cairncross; B Cox; C Forster; A F Wren
Journal:  Psychoneuroendocrinology       Date:  1979-07       Impact factor: 4.905

8.  The effect of unilateral amygdala lesion on the imipramine action in behavioural despair in rats.

Authors:  Z Górka; K Ossowska; R Stach
Journal:  J Pharm Pharmacol       Date:  1979-09       Impact factor: 3.765

9.  Kindling in olfactory-lesioned rats.

Authors:  D P Cain; M E Corcoran
Journal:  Behav Biol       Date:  1978-02

10.  Functional organization of the rat amygdala with respect to avoidance behavior.

Authors:  S P Grossman; L Grossman; L Walsh
Journal:  J Comp Physiol Psychol       Date:  1975-02
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  4 in total

1.  Fluoxetine enhances memory processing in mice.

Authors:  J F Flood; A Cherkin
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

2.  Memory disorders associated with consumption of drugs: updating through a case/noncase study in the French PharmacoVigilance Database.

Authors:  Francois Chavant; Sylvie Favrelière; Claire Lafay-Chebassier; Caroline Plazanet; Marie-Christine Pérault-Pochat
Journal:  Br J Clin Pharmacol       Date:  2011-12       Impact factor: 4.335

Review 3.  Safety of pharmacotherapy options for bulimia nervosa and binge eating disorder.

Authors:  Nicholas T Bello; Bryn L Yeomans
Journal:  Expert Opin Drug Saf       Date:  2017-10-31       Impact factor: 4.250

4.  A role for the extended amygdala in the fear-enhancing effects of acute selective serotonin reuptake inhibitor treatment.

Authors:  S Ravinder; N S Burghardt; R Brodsky; E P Bauer; S Chattarji
Journal:  Transl Psychiatry       Date:  2013-01-15       Impact factor: 6.222
  4 in total

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