Literature DB >> 6790863

Estimation of energy metabolism in human skeletal muscle homogenate as a diagnostic aid.

W Ruitenbeek, R C Sengers, J M Trijbels, A M Stadhouders, A J Janssen.   

Abstract

A method is presented for the in vitro testing of the energy metabolism of human skeletal muscle. The levels of creatine phosphate, ATP, ADP and AMP, which are defined by the activity of many enzyme system, are measured after incubation of the muscle homogenate with various substrates in the presence or absence of specific inhibitors. Detection of abnormal metabolite concentrations is important for diagnosis of patients with myopathic syndromes.

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Year:  1981        PMID： 6790863     DOI： 10.1007/BF02263606

Source DB:  PubMed          Journal:  J Inherit Metab Dis        ISSN： 0141-8955            Impact factor:   4.982


  1 in total

1.  Pyruvate oxidation in rat and human skeletal muscle mitochondria.

Authors:  H Bookelman; J M Trijbels; R C Sengers; A J Janssen; J H Veerkamp; A M Stadhouders
Journal:  Biochem Med       Date:  1978-12
  1 in total
  6 in total

1.  A mitochondrial encephalomyopathy with a partial cytochrome c oxidase deficiency of muscle.

Authors:  P M Van Erven; F J Gabreëls; W Ruitenbeek; W O Renier; H J Ter Laak; A M Stadhouders
Journal:  J Neurol Neurosurg Psychiatry       Date:  1988-05       Impact factor: 10.154

Review 2.  Disorders of the mitochondrial respiratory chain: clinical manifestations and diagnostic approach.

Authors:  J M Trijbels; R C Sengers; W Ruitenbeek; J C Fischer; J A Bakkeren; A J Janssen
Journal:  Eur J Pediatr       Date:  1988-11       Impact factor: 3.183

Review 3.  Mitochondrial myopathies. Clinical, morphological and biochemical aspects.

Authors:  R C Sengers; A M Stadhouders; J M Trijbels
Journal:  Eur J Pediatr       Date:  1984-02       Impact factor: 3.183

4.  Familial Leigh's syndrome: association with a defect in oxidative metabolism probably restricted to brain.

Authors:  P M van Erven; F J Gabreëls; W Ruitenbeek; W O Renier; K J Lamers; J L Sloof
Journal:  J Neurol       Date:  1987-05       Impact factor: 4.849

5.  Demyelination and disturbed metabolism of pyruvate: a case report.

Authors:  R C Sengers; J M Trijbels; J A Bakkeren; W Ruitenbeek; A J Janssen; A M Stadhouders; H J ter Laak
Journal:  Eur J Pediatr       Date:  1983-04       Impact factor: 3.183

6.  A mitochondrial encephalomyopathy: the first case with an established defect at the level of coenzyme Q.

Authors:  J C Fischer; W Ruitenbeek; F J Gabreëls; A J Janssen; W O Renier; R C Sengers; A M Stadhouders; H J ter Laak; J M Trijbels; J H Veerkamp
Journal:  Eur J Pediatr       Date:  1986-02       Impact factor: 3.183
  6 in total

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