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Literature DB >> 6790623

Unusual phenotypes of human inducer T cells as measured by OKT4 and related monoclonal antibodies.

M A Bach, F Phan-Dinh-Tuy, J F Bach, D Wallach, W E Biddison, S O Sharrow, G Goldstein, P C Kung.

Abstract

OKT4, a murine monoclonal antibody, was previously shown to react with inducer/helper T cells in man. We now report the absence of this reactivity in 2 subjects of African ancestry and the production of 4 new monoclonal antibodies (OKT4A-D) that detect distinct antigens on human inducer/helper T cells.

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Year: 1981 PMID： 6790623

Source DB: PubMed Journal: J Immunol ISSN： 0022-1767 Impact factor: 5.422

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Cited

13 in total

1. Single amino acid substitution in the V3 domain of CD4 is responsible for OKT4 epitope deficiency.

Authors: S Tokito; S Kishi; R Yamamoto; T Takenaka; H Nakauchi
Journal: Immunogenetics Date: 1991 Impact factor: 2.846

2. Flow cytometry analysis of OKT4 epitope deficiency in South African black children.

Authors: E J Hughes; E A Goddard; P Bouic; D W Beatty
Journal: Clin Exp Immunol Date: 1994-12 Impact factor: 4.330

3. Hereditary CD4+ T lymphocytopenia.

Authors: S Freier; E Kerem; Z Dranitzki; M Schlesinger; R Rabinowitz; C Brautbar; M Ashkirat; Y Naparstek
Journal: Arch Dis Child Date: 1998-04 Impact factor: 3.791

4. Polymorphism for RhT3, a CD3-like cell surface antigen, expressed on rhesus monkey T lymphocytes.

Authors: F J Nooij; W van Vreeswijk; J Coolen
Journal: Immunology Date: 1986-12 Impact factor: 7.397

5. Specific cellular immune response and neutralizing antibodies in goats immunized with native or recombinant envelope proteins derived from human T-lymphotropic virus type IIIB and in human immunodeficiency virus-infected men.

Authors: K Krohn; W G Robey; S Putney; L Arthur; P Nara; P Fischinger; R C Gallo; F Wong-Staal; A Ranki
Journal: Proc Natl Acad Sci U S A Date: 1987-07 Impact factor: 11.205

Unusual phenotypes of human inducer T cells as measured by OKT4 and related monoclonal antibodies.

1. Single amino acid substitution in the V3 domain of CD4 is responsible for OKT4 epitope deficiency.

2. Flow cytometry analysis of OKT4 epitope deficiency in South African black children.

3. Hereditary CD4+ T lymphocytopenia.

4. Polymorphism for RhT3, a CD3-like cell surface antigen, expressed on rhesus monkey T lymphocytes.

5. Specific cellular immune response and neutralizing antibodies in goats immunized with native or recombinant envelope proteins derived from human T-lymphotropic virus type IIIB and in human immunodeficiency virus-infected men.

6. The clinical use of monoclonal anti-T-cell antibodies.

7. The T cell antigen receptor CD3:CD4 molecular complex is diminished on the surface of pulmonary lymphocytes.

8. Hereditary deficiency of OKT4-positive cells: studies for mode of inheritance and lymphocyte functions.

9. Hereditary abnormalities of the OKT4 human lymphocyte epitope in two families.

10. Tumor cell line characterization of a malignant histiocytosis transplanted into nude mice.