Comparison of a new 10% and 20% safflower oil fat emulsion in pediatric parenteral nutrition.

A new 20% safflower oil fat emulsion was compared with its 10% counterpart in a small series of pediatric patients. Five infants and children, studied for a 2-week period, received either the 10% or 20% emulsion for 1 week and the other emulsion the 2nd week. No serious toxicity or side effects were noted in any of the patients following the infusion of either emulsion. In addition, significant weight gain was noted in the children, and clinical improvement was apparent in all cases. This preliminary study suggests that the 20% Liposyn is as safe and effective as its 10% counterpart.