Literature DB >> 6788746

Sensitivity of gonococci to rosoxacin compared with that of penicillin, cefuroxime and tetracycline.

A D Seth.   

Abstract

The in vitro activity of rosoxacin, a pyridyl quinolone derivative against Neisseria gonorrhoeae is compared with that of penicillin, cefuroxime and tetracycline. Three groups of gonococci comprising of beta-lactamase-positive and negative strains and gonococci with high penicillin MICs are studied. Rosoxacin was the most active against the entire spectrum of gonococci tested in vitro and its activity is not affected by the production of beta-lactamase by some gonococci.

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Year:  1981        PMID： 6788746     DOI： 10.1093/jac/7.4.331

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  5 in total

1.  Influence of inoculum size on comparative susceptibilities of penicillinase-positive and -negative Neisseria gonorrhoeae to 31 antimicrobial agents.

Authors:  W H Hall; B J Opfer
Journal:  Antimicrob Agents Chemother       Date:  1984-08       Impact factor: 5.191

2.  In vitro susceptibility and cross-resistance of South African isolates of Neisseria gonorrhoeae to 14 antimicrobial agents.

Authors:  L D Liebowitz; R C Ballard; H J Koornhof
Journal:  Antimicrob Agents Chemother       Date:  1982-10       Impact factor: 5.191

3.  Treatment of uncomplicated gonorrhoea with rosoxacin (acrosoxacin).

Authors:  K B Lim; V S Rajan; Y C Giam; E O Lui; E H Sng; K L Yeo
Journal:  Br J Vener Dis       Date:  1984-06

4.  Rosoxacin in the treatment of uncomplicated gonorrhoea in men.

Authors:  K Panikabutra; C Ariyarit; A Chitwarakorn; C Saensanoh
Journal:  Br J Vener Dis       Date:  1984-08

5.  Quinolone derivative, flumequine, as short-term treatment for gonorrhoea.

Authors:  H B Svindland; P L Svarva; J A Maeland
Journal:  Br J Vener Dis       Date:  1982-10
  5 in total

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