Literature DB >> 6788684

Monoclonal antibodies to human syncytiotrophoblast.

C A Sunderland, C W Redman, G M Stirrat.   

Abstract

Two monoclonal antibodies, NDOG1 and NDOG2, have been produced which are directed towards human syncytiotrophoblast. The antigens detected by these antibodies are absent from human liver, heart, kidney, brain and from normal human sera. The NDOG1 antigen but not NDOG2 antigen is a component of pregnancy sera and falls to undetectable levels within 6 hours of placental delivery. This molecule is not human chorionic gonadotrophin, human placental lactogen, placental alkaline phosphatase. SP1 or PAPP-A. Immunoperoxidase staining shows that both antigens are on apical aspects of the syncytiotrophoblast and not in the villous stroma.

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Year:  1981        PMID： 6788684      PMCID： PMC1555034     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  19 in total

1.  Circulating levels of pregnancy-specific beta1-glycoprotein and human placental lactogen in the third trimester of pregnancy: their relationship to parity, birth weight, and placental weight.

Authors:  Y B Gordon; J G Grudzinskas; J D Lewis; D Jeffrey; A T Letchworth
Journal:  Br J Obstet Gynaecol       Date:  1977-09

2.  Glycoproteins and antigens of membranes prepared from rat thymocytes after lysis by shearing or with the detergent Tween-40.

Authors:  R Standring; A F Williams
Journal:  Biochim Biophys Acta       Date:  1978-03-21

3.  Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes.

Authors:  A F Williams; G Galfrè; C Milstein
Journal:  Cell       Date:  1977-11       Impact factor: 41.582

4.  Distribution of MHC antigens in human placental chorionic villi.

Authors:  W P Faulk; A R Sanderson; A Temple
Journal:  Transplant Proc       Date:  1977-06       Impact factor: 1.066

5.  Preparation of human placental villous surface membrane.

Authors:  N C Smith; M G Brush; S Luckett
Journal:  Nature       Date:  1974-11-22       Impact factor: 49.962

6.  Expression of HLA system antigens on placenta.

Authors:  P N Goodfellow; C J Barnstable; W F Bodmer; D Snary; M J Crumpton
Journal:  Transplantation       Date:  1976-12       Impact factor: 4.939

7.  Distribution of beta2 microglobulin and HLA in chorionic villi of human placentae.

Authors:  W P Faulk; A Temple
Journal:  Nature       Date:  1976-08-26       Impact factor: 49.962

8.  Alkaline phosphatase in maternal and fetal sera at term and during the puerperium.

Authors:  P N Kitchener; F C Neale; S Posen; J Brudenell-Woods
Journal:  Am J Clin Pathol       Date:  1965-12       Impact factor: 2.493

9.  Derivation of specific antibody-producing tissue culture and tumor lines by cell fusion.

Authors:  G Köhler; C Milstein
Journal:  Eur J Immunol       Date:  1976-07       Impact factor: 5.532

10.  Serum human chorionic gonadotropin levels throughout normal pregnancy.

Authors:  G D Braunstein; J Rasor; H Danzer; D Adler; M E Wade
Journal:  Am J Obstet Gynecol       Date:  1976-11-15       Impact factor: 8.661
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  8 in total

1.  Cell surface antigens of human trophoblast: definition of an apparently unique system with a monoclonal antibody.

Authors:  U W Mueller; C S Hawes; W R Jones
Journal:  Immunology       Date:  1986-09       Impact factor: 7.397

2.  Class 1 major histocompatibility complex antigens on human extra-villous trophoblast.

Authors:  C W Redman; A J McMichael; G M Stirrat; C A Sunderland; A Ting
Journal:  Immunology       Date:  1984-07       Impact factor: 7.397

3.  Macrophage populations in the human placenta and amniochorion.

Authors:  J N Bulmer; P M Johnson
Journal:  Clin Exp Immunol       Date:  1984-08       Impact factor: 4.330

4.  Isolation and characterisation of a hyaluronan binding protein, hyaluronectin, from human placenta and its colocalisation with hyaluronan.

Authors:  J M Ponting; S Kumar
Journal:  J Anat       Date:  1995-02       Impact factor: 2.610

5.  Proteoglycans in haemodialysis-related amyloidosis.

Authors:  K Ohashi; M Hara; M Yanagishita; R Kawai; S Tachibana; Y Ogura
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064

6.  Identification of extra-villous trophoblast cells in human decidua using an apparently unique murine monoclonal antibody to trophoblast.

Authors:  U W Mueller; C S Hawes; W R Jones
Journal:  Histochem J       Date:  1987-05

7.  A vascular endothelial cell antigen with restricted distribution in human foetal, adult and malignant tissues.

Authors:  Y C Cui; P C Tai; K C Gatter; D Y Mason; C J Spry
Journal:  Immunology       Date:  1983-05       Impact factor: 7.397

8.  A 72 kD trophoblast glycoprotein defined by a monoclonal antibody.

Authors:  N Hole; P L Stern
Journal:  Br J Cancer       Date:  1988-03       Impact factor: 7.640
  8 in total

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