Literature DB >> 6787978

In vitro comparison of dibekacin and gentamicin activities.

C D Hill, G W Counts, M Turck.   

Abstract

Dibekacin, a new parenteral aminoglycoside, was compared with gentamicin in vitro against 221 clinical isolates. Tests for minimum inhibitory concentrations, performed in agar, demonstrated that dibekacin was comparable to gentamicin against most isolates tested. Dibekacin was slightly more active than gentamicin against some isolates of Pseudomonas aeruginosa, but was significantly less active against strains of Serratia.

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Year:  1981        PMID： 6787978      PMCID： PMC181381          DOI： 10.1128/AAC.19.1.190

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  Phosphorylative inactivation of aminoglycosidic antibiotics by Escherichia coli carrying R factor.

Authors:  H Umezawa; M Okanishi; S Kondo; K Hamana; R Utahara; K Maeda; S Mitsuhashi
Journal:  Science       Date:  1967-09-29       Impact factor: 47.728

2.  Gentamicin resistance in strains of Pseudomonas aeruginosa mediated by enzymatic N-acetylation of the deoxystreptamine moiety.

Authors:  M Brzezinska; R Benveniste; J Davies; P J Daniels; J Weinstein
Journal:  Biochemistry       Date:  1972-02-29       Impact factor: 3.162

3.  Enzymatic inactivation of gentamicin C components by cell-free extract from Pseudomonas aeruginosa.

Authors:  S Mitsuhashi; F Kobayashi; M Yamaguchi
Journal:  J Antibiot (Tokyo)       Date:  1971-06       Impact factor: 2.649

4.  3',4'-dideoxy-kanamycin B active against kanamycin-resistant Escherichia coli and Pseudomonas aeruginosa.

Authors:  H Umezawa; S Umezawa; T Tsuchiya; Y Okazaki
Journal:  J Antibiot (Tokyo)       Date:  1971-07       Impact factor: 2.649

5.  In vitro comparison of kanamycin, kanendomycin, gentamicin, amikacin, sisomicin, and dibekacin against 200 strains of Pseudomonas aeruginosa.

Authors:  A G Paradelis; J Douboyas; G Stathopoulos; A Grigoriadou-Edipides; C Triantaphylidis; J Papapanagiotou
Journal:  Antimicrob Agents Chemother       Date:  1978-09       Impact factor: 5.191

6.  Cefazaflur, a new parenteral cephalosporin: in vitro studies.

Authors:  G W Counts; D Gregory; D Zeleznik; M Turch
Journal:  Antimicrob Agents Chemother       Date:  1977-04       Impact factor: 5.191
  6 in total
  2 in total

Review 1.  Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use.

Authors:  P Noone
Journal:  Drugs       Date:  1984-06       Impact factor: 9.546

2.  In vitro comparison of aminoglycoside activities and their synergistic action with piperacillin.

Authors:  J A Hoogkamp-Korstanje
Journal:  Infection       Date:  1985 Jan-Feb       Impact factor: 3.553
  2 in total

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