Literature DB >> 6787571

Chromatographic and biologic analysis of ME and OVLT LHRH.

W K Samson, G Snyder, C P Fawcett, S M McCann.   

Abstract

The luteinizing hormone (LH)-releasing activities a pooled rat organum vasculosum lamina terminalis (OVLT) and median eminence (ME) tissues were evaluated for chromatographic and biologic similarity and compared to those of synthetic decapeptide LH-releasing hormone (LHRH). The LHRH detected in these extracts appeared similar chromatographically (Sephadex G-25) to synthetic LHRH. These extracts, as well as synthetic LHRH, were also capable of stimulating dose dependent gonadotropin release form cultures rat gonadotrophs. These findings suggest a physiological role of the LHRH present in the rat OVLT in the control of gonadotropin secretion.

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Year:  1980        PMID： 6787571     DOI： 10.1016/0196-9781(80)90041-8

Source DB:  PubMed          Journal:  Peptides        ISSN： 0196-9781            Impact factor:   3.750


  5 in total

1.  A hypothalamic follicle-stimulating hormone-releasing decapeptide in the rat.

Authors:  W H Yu; S Karanth; A Walczewska; S A Sower; S M McCann
Journal:  Proc Natl Acad Sci U S A       Date:  1997-08-19       Impact factor: 11.205

2.  Gonadotropin-releasing hormone neurons in the preoptic-hypothalamic region of the rat contain lamprey gonadotropin-releasing hormone III, mammalian luteinizing hormone-releasing hormone, or both peptides.

Authors:  J K Hiney; S A Sower; W H Yu; S M McCann; W L Dees
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-12       Impact factor: 11.205

Review 3.  Progress in neuroendocrinology: LH releasing (LHRH), basic and clinical aspects.

Authors:  S M McCann
Journal:  J Endocrinol Invest       Date:  1983-06       Impact factor: 4.256

4.  The localisation of LH-RH neurones in the diencephalon of the domestic hen.

Authors:  R J Sterling; P J Sharp
Journal:  Cell Tissue Res       Date:  1982       Impact factor: 5.249

Review 5.  Understanding peptide biology: The discovery and characterization of the novel hormone, neuronostatin.

Authors:  Gina L C Yosten; Mollisa M Elrick; Alison Salvatori; Lauren M Stein; Grant R Kolar; Jun Ren; John A Corbett; Willis K Samson
Journal:  Peptides       Date:  2015-06-04       Impact factor: 3.750
  5 in total

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