Mucoepidermoid-adenosquamous carcinoma of the larynx and hypopharynx: a report of 21 cases and a review of the literature.

Twenty-one cases of mucoepidermoid-adenosquamous carcinoma (MEC/ASC) of the larynx and hypopharynx were collected and reviewed from the Armed Forces Institute of Pathology tumor registry from 1945 to 1979. This is the largest series of such lesions in this location reported to date. In addition, the literature was reviewed and 32 previous cases noted. The overall five-year survival was 77%, although low-grade mucoepidermoid carcinoma had a better survival than did adenosquamous-high-grade mucoepidermoid carcinoma.