Literature DB >> 6787360

Lactoperoxidase-catalyzed iodination of arachidonic acid: formation of macrolides.

J M Boeynaems, D Reagan, W C Hubbard.   

Abstract

In the presence of iodide and hydrogen peroxide, lactoperoxidase catalyzed the conversion of arachidonic acid into several iodinated products; the major one was previously identified as an iodo-delta-lactone. Two minor and less polar products have now been characterized as 15-iodo-14-hydroxyeicosatrienoic acid, omega-lactone and 14-iodo-15-hydroxyeicosatrienoic acid, omega-lactone, on the basis of 125I incorporation, mass spectrometry, proton magnetic resonance spectroscopy and chemical modifications.

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Year:  1981        PMID： 6787360     DOI： 10.1007/BF02535024

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  9 in total

1.  Topographical arrangement of membrane proteins in the intact myelin sheath. Lactoperoxidase incorproation of iodine into myelin surface proteins.

Authors:  J F Poduslo; P E Braun
Journal:  J Biol Chem       Date:  1975-02-10       Impact factor: 5.157

2.  Identification by nuclear magnetic resonance of iodinated lipids in the dog thyroid.

Authors:  J L Rabinowitz; M Zanger; V Podolski
Journal:  Biochem Biophys Res Commun       Date:  1976-02-23       Impact factor: 3.575

3.  Lactoperoxidase-catalyzed iodination of surface membrane lipids.

Authors:  M Mersel; A Benenson; F Doljanski
Journal:  Biochem Biophys Res Commun       Date:  1976-06-21       Impact factor: 3.575

4.  Use of lactoperoxidase catalyzed iodination in immunochemical studies.

Authors:  M Morrison; G S Bayse; R G Webster
Journal:  Immunochemistry       Date:  1971-03

5.  Enzymatic radioiodination of phospholipids catalyzed by lactoperoxidase.

Authors:  A Benenson; M Mersel; A Pinson; M Heller
Journal:  Anal Biochem       Date:  1980-01-15       Impact factor: 3.365

6.  Surface labelling for human tumour KB cells. Iodination and fractionation of membrane glycoproteins.

Authors:  T D Butters; R C Hughes
Journal:  Biochem J       Date:  1975-07       Impact factor: 3.857

7.  Specific 125I-iodination of cell surface lipids: plasma membrane alterations induced during humoral immune attack.

Authors:  S I Schlager
Journal:  J Immunol       Date:  1979-11       Impact factor: 5.422

8.  Iodinated phospholipids and the in vitro iodination of proteins of dog thyroid gland.

Authors:  J L Rabinowitz; C J Tavares
Journal:  Biochem J       Date:  1977-11-15       Impact factor: 3.857

9.  Transformation of arachidonic acid into an iodolactone by the rat thyroid.

Authors:  J M Boeynaems; W C Hubbard
Journal:  J Biol Chem       Date:  1980-10-10       Impact factor: 5.157
  9 in total

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