Uptake of lysosomal enzymes by human fibroblasts: lack of uptake of fungal or plant glycosidases in comparison with a mammalian enzyme.

alpha-Galactosidase from human placenta was actively taken up by cultured fibroblasts from patients with Fabry's disease whereas the enzyme from the fig was not absorbed. alpha-Glucosidase from two microbiological sources. A. fumigatus and A. niger, was not taken up by cultured fibroblasts from patients with Pompe's disease.