Literature DB >> 6787113

Immunohistochemical localization of dipeptidyl aminopeptidase IV in rat kidney, liver, and salivary glands.

K M Fukasawa, K Fukasawa, N Sahara, M Harada, Y Kondo, I Nagatsu.   

Abstract

Specific antibodies directed against dipeptidyl aminopeptidase (DAP) IV prepared from rat and pig kidneys were produced in rabbits. Using a peroxidase-labeled or fluorescein isothiocyanate-labeled antibody method, localization of DAP IV was investigated in various tissues of the rat (kidney, liver and salivary glands). DAP IV was mainly localized in the brush border of the proximal tubules (kidney), in the cell membrane around bile canaliculi of hepatic cells (liver), and in the cell membrane of serous acinar cells (parotid and submaxillary glands). These results substantiate that DAP IV is a membrane-bound peptidase.

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Year:  1981        PMID： 6787113     DOI： 10.1177/29.3.6787113

Source DB:  PubMed          Journal:  J Histochem Cytochem        ISSN： 0022-1554            Impact factor:   2.479


  25 in total

1.  Dipeptidyl peptidases in the soleus muscle of the rat before and after treatment with 5-hydroxytryptamine.

Authors:  P J Stoward; K N Christie; C Thomson
Journal:  Histochemistry       Date:  1988

2.  Lateral diffusion of luminal membrane components during secretion in parotid acinar cells of the rat. Immunocytochemical and freeze-fracture studies.

Authors:  N Sahara; K Suzuki
Journal:  Cell Tissue Res       Date:  1990-09       Impact factor: 5.249

3.  Dipeptidyl peptidase IV--subcellular localization, activity and kinetics in lymphocytes from control subjects, immunodeficient patients and cord blood.

Authors:  C Harland; T Shah; A D Webster; T J Peters
Journal:  Clin Exp Immunol       Date:  1988-11       Impact factor: 4.330

4.  Therapeutic vaccine against DPP4 improves glucose metabolism in mice.

Authors:  Zhengda Pang; Hironori Nakagami; Mariana K Osako; Hiroshi Koriyama; Futoshi Nakagami; Hideki Tomioka; Munehisa Shimamura; Hitomi Kurinami; Yoichi Takami; Ryuichi Morishita; Hiromi Rakugi
Journal:  Proc Natl Acad Sci U S A       Date:  2014-03-17       Impact factor: 11.205

5.  The organ distribution of gp-330 (Heymann antigen) and gp-90 in the mouse and the rat.

Authors:  K J Assmann; W P Lange; M M Tangelder; R A Koene
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

6.  Characterization of a soluble form of dipeptidyl peptidase IV from pig liver.

Authors:  K M Fukasawa; K Fukasawa; B Y Hiraoka; M Harada
Journal:  Experientia       Date:  1983-09-15

Review 7.  Cytochemistry of membrane proteases.

Authors:  R Gossrau
Journal:  Histochem J       Date:  1985-07

8.  Ultrastructural localization of dipeptidyl peptidase IV in rat salivary glands by immunocytochemistry.

Authors:  N Sahara; K Suzuki
Journal:  Cell Tissue Res       Date:  1984       Impact factor: 5.249

Review 9.  [Has dipeptidyl peptidase IV an effect on blood pressure and coagulation?].

Authors:  E Heymann; R Mentlein
Journal:  Klin Wochenschr       Date:  1984-01-02

10.  Palmar fibromatosis (Dupuytren's contracture). Ultrastructural and enzyme histochemical studies of 43 cases.

Authors:  H Iwasaki; H Müller; H J Stutte; U Brennscheidt
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1984
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