Literature DB >> 6786603

Haloperidol secreted in breast milk.

L J Whalley, P G Blain, J K Prime.   

Abstract

A nursing mother was given haloperidol 5 mg twice daily for puerperal psychosis and continued to breast feed under hospital supervision. Despite considerable amounts of haloperidol being secreted in the breast milk (up to 23.5 micrograms/l), the infant was apparently not sedated, fed well, and continued to thrive. The findings suggest that maternal ingestion of haloperidol for short periods has no deleterious effect on the infant's development.

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Year:  1981        PMID: 6786603      PMCID: PMC1505716          DOI: 10.1136/bmj.282.6278.1746

Source DB:  PubMed          Journal:  Br Med J (Clin Res Ed)        ISSN: 0267-0623


  2 in total

1.  Abnormal ontogeny in young rabbits after chronic administration of haloperidol to the nursing mothers.

Authors:  P Lundborg
Journal:  Brain Res       Date:  1972-09-29       Impact factor: 3.252

2.  Haloperidol excretion in human milk.

Authors:  R B Stewart; B Karas; P K Springer
Journal:  Am J Psychiatry       Date:  1980-07       Impact factor: 18.112

  2 in total
  9 in total

Review 1.  Antipsychotics and breast-feeding: a review of the literature.

Authors:  T Tényi; G Csábi; M Trixler
Journal:  Paediatr Drugs       Date:  2000 Jan-Feb       Impact factor: 3.022

Review 2.  The quality of lactation studies including antipsychotics.

Authors:  Hazel Hummels; Daphne Bertholee; Douwe van der Meer; Jan Pieter Smit; Bob Wilffert; Peter Ter Horst
Journal:  Eur J Clin Pharmacol       Date:  2016-08-24       Impact factor: 2.953

3.  The potential risks of commonly prescribed antipsychotics: during pregnancy and lactation.

Authors:  Mohammad Masud Iqbal; Alka Aneja; Atiq Rahman; James Megna; Wanda Freemont; Mohammed Shiplo; Nikil Nihilani; Kathy Lee
Journal:  Psychiatry (Edgmont)       Date:  2005-08

Review 4.  A guide to the safety of CNS-active agents during breastfeeding.

Authors:  C A Chisholm; J A Kuller
Journal:  Drug Saf       Date:  1997-08       Impact factor: 5.606

Review 5.  Haloperidol decanoate. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in psychosis.

Authors:  R Beresford; A Ward
Journal:  Drugs       Date:  1987-01       Impact factor: 9.546

Review 6.  Drugs in human milk. Clinical pharmacokinetic considerations.

Authors:  H C Atkinson; E J Begg; B A Darlow
Journal:  Clin Pharmacokinet       Date:  1988-04       Impact factor: 6.447

Review 7.  Principles of drug biodisposition in the neonate. A critical evaluation of the pharmacokinetic-pharmacodynamic interface (Part I).

Authors:  J B Besunder; M D Reed; J L Blumer
Journal:  Clin Pharmacokinet       Date:  1988-04       Impact factor: 6.447

Review 8.  Excretion of psychoactive drugs into breast milk. Pharmacokinetic principles and recommendations.

Authors:  G Pons; E Rey; I Matheson
Journal:  Clin Pharmacokinet       Date:  1994-10       Impact factor: 6.447

9.  Zuclopenthixol levels in serum and breast milk.

Authors:  T Aaes-Jørgensen; F Bjørndal; U Bartels
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

  9 in total

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