Literature DB >> 6785258

High-dose intravenous gammaglobulin therapy of refractory, in particular idiopathic thrombocytopenia in childhood.

P Imbach, S Barandun, C Baumgartner, A Hirt, F Hofer, H P Wagner.   

Abstract

A new immunoglobulin (Ig) for intravenous use was given in high doses to 4 children with refractory idiopathic thrombocytopenic purpura (ITP) and 2 children with idiopathic aplastic anemia (IAA). Within 5-10 days after initiation of Ig therapy the platelets of the children with ITP rose to 300,000-650,000/mm3 and could be maintained at normal levels with one Ig infusion every 1-3 weeks. No reaction was observed in the 2 patients with IAA.

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Year:  1981        PMID: 6785258

Source DB:  PubMed          Journal:  Helv Paediatr Acta        ISSN: 0018-022X


  29 in total

1.  Fcγ receptor expression on splenic macrophages in adult immune thrombocytopenia.

Authors:  S Audia; K Santegoets; A G Laarhoven; G Vidarsson; O Facy; P Ortega-Deballon; M Samson; N Janikashvili; P Saas; B Bonnotte; T R Radstake
Journal:  Clin Exp Immunol       Date:  2017-02-28       Impact factor: 4.330

Review 2.  Fc glycan-modulated immunoglobulin G effector functions.

Authors:  Isaak Quast; Jan D Lünemann
Journal:  J Clin Immunol       Date:  2014-04-24       Impact factor: 8.317

Review 3.  Intravenous immunoglobulin (IVIG) for the therapy of autoimmune disorders.

Authors:  S A Schwartz
Journal:  J Clin Immunol       Date:  1990-03       Impact factor: 8.317

Review 4.  Mechanism of action of intravenous immunoglobulin in immune-mediated cytopenias.

Authors:  H I Atrah; R J Davidson
Journal:  J Clin Pathol       Date:  1988-12       Impact factor: 3.411

5.  Treatment of idiopathic thrombocytopenic purpura.

Authors:  I A Warrier
Journal:  Indian J Pediatr       Date:  1986 Nov-Dec       Impact factor: 1.967

6.  Cyclophosphamide-induced immune thrombocytopenia in a patient with ovarian carcinoma successfully treated with intravenous gamma globulin.

Authors:  C Mueller-Eckhardt; E Küenzlen; V Kiefel; H Vahrson; M Graubner
Journal:  Blut       Date:  1983-03

7.  High-dose intravenous therapy with immune globulin before delivery for idiopathic thrombocytopenic purpura.

Authors:  R J Adderley; P C Rogers; D Shaw; L D Wadsworth
Journal:  Can Med Assoc J       Date:  1984-04-01       Impact factor: 8.262

8.  IVMP+IVIG raises platelet counts faster than IVIG alone: results of a randomized, blinded trial in childhood ITP.

Authors:  Manuel Carcao; Mariana Silva; Michele David; Robert J Klaassen; MacGregor Steele; Victoria Price; Cindy Wakefield; Lussia Kim; Derek Stephens; Victor S Blanchette
Journal:  Blood Adv       Date:  2020-04-14

9.  Overview of the pathogenesis and treatment of chronic inflammatory demyelinating polyneuropathy with intravenous immunoglobulins.

Authors:  Mohamed Mahdi-Rogers; Yusuf A Rajabally
Journal:  Biologics       Date:  2010-03-24

10.  Immunoglobulins in adult sepsis and septic shock.

Authors:  Susanne Toussaint; Herwig Gerlach
Journal:  Curr Infect Dis Rep       Date:  2012-10       Impact factor: 3.725

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