Literature DB >> 6785059

Aciclovir and trifluorothymidine in herpetic keratitis. Preliminary report of a multicentered trial.

C la Lau, J A Oosterhuis, J Versteeg, G van Rij, J G Renardel de Lavalette, A Craandijk, W R Lamers, T Mierlobensteyn.   

Abstract

The efficacy of Aciclovir and Trifluorothymidine (TFT) treatment was tested in a double blind trial of thirty-eight patients with dendritic keratitis. All twenty patients treated with Aciclovir healed within 10 days with an average healing time of 5.0 days. Two of the eighteen patients treated with TFT failed to heal within 22 days, the others healed within ten days, the average healing was 6.6 days. Punctate keratopathy was seen in 70% of both groups. Intense conjunctival hyperaemia developed in two TFT patients.

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Year:  1981        PMID: 6785059     DOI: 10.1007/BF00158011

Source DB:  PubMed          Journal:  Doc Ophthalmol        ISSN: 0012-4486            Impact factor:   2.379


  9 in total

1.  Acyclic antimetabolite therapy of experimental herpes simplex keratitis.

Authors:  D Pavan-Langston; R Campbell; J Lass
Journal:  Am J Ophthalmol       Date:  1978-11       Impact factor: 5.258

2.  Clinical evaluation of trifluorothymidine in the treatment of herpes simplex corneal ulcers.

Authors:  P C Wellings; P N Awdry; F H Bors; B R Jones; D C Brown; H E Kaufman
Journal:  Am J Ophthalmol       Date:  1972-06       Impact factor: 5.258

3.  Poly I:C in herpetic keratitis in rabbits.

Authors:  J A Oosterhuis; W A Nolen; S H Sie; J Versteeg
Journal:  Exp Eye Res       Date:  1974-04       Impact factor: 3.467

4.  Trifluridine in resistant human herpetic keratitis.

Authors:  R A Hyndiuk; R E Charlin; T V Alpren; R O Schultz
Journal:  Arch Ophthalmol       Date:  1978-10

5.  Treatment of experimental herpes simplex keratitis with acycloguanosine.

Authors:  D J Bauer; P Collins; W E Tucker; A W Macklin
Journal:  Br J Ophthalmol       Date:  1979-06       Impact factor: 4.638

6.  Antiviral update.

Authors:  H E Kaufman
Journal:  Ophthalmology       Date:  1979-01       Impact factor: 12.079

7.  Treatment of amoeboid herpetic ulcers with adenine arabinoside or trifluorothymidine.

Authors:  D J Coster; B R Jones; J I McGill
Journal:  Br J Ophthalmol       Date:  1979-06       Impact factor: 4.638

8.  The activity in vitro against herpes virus of 9-(2-hydroxyethoxymethyl)guanine (acycloguanosine), a new antiviral agent.

Authors:  P Collins; D J Bauer
Journal:  J Antimicrob Chemother       Date:  1979-07       Impact factor: 5.790

9.  Efficacy of acycloguanosine (Wellcome 248U) against herpes-simplex corneal ulcers.

Authors:  B R Jones; D J Coster; P N Fison; G M Thompson; L M Cobo; M G Falcon
Journal:  Lancet       Date:  1979-02-03       Impact factor: 79.321

  9 in total
  8 in total

Review 1.  Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.

Authors:  Kirk R Wilhelmus
Journal:  Cochrane Database Syst Rev       Date:  2015-01-09

2.  Acyclovir and trifluorothymidine in herpetic keratitis: a multicentre trial.

Authors:  C la Lau; J A Oosterhuis; J Versteeg; G van Rij; J G Renardel de Lavalette; A Craandijk; W P Lamers; W P Lamers
Journal:  Br J Ophthalmol       Date:  1982-08       Impact factor: 4.638

3.  The treatment of herpes simplex virus epithelial keratitis.

Authors:  K R Wilhelmus
Journal:  Trans Am Ophthalmol Soc       Date:  2000

Review 4.  Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis.

Authors:  Kirk R Wilhelmus
Journal:  Cochrane Database Syst Rev       Date:  2010-12-08

5.  A randomised double-blind clinical trial of acyclovir (Zovirax) and adenine arabinoside in herpes simplex corneal ulceration.

Authors:  B J Young; A Patterson; T Ravenscroft
Journal:  Br J Ophthalmol       Date:  1982-06       Impact factor: 4.638

6.  Acyclovir treatment in stromal herpetic keratitis.

Authors:  J A Oosterhuis; R van Ganswijk; J Versteeg
Journal:  Doc Ophthalmol       Date:  1983-12-15       Impact factor: 2.379

7.  Acyclovir treatment in stromal herpetic keratitis.

Authors:  R van Ganswijk; J A Oosterhuis; M Swart-van den Berg; J Versteeg
Journal:  Doc Ophthalmol       Date:  1983-02-28       Impact factor: 2.379

8.  Acute Herpetic Keratitis: What is the Role for Ganciclovir Ophthalmic Gel?

Authors:  Afsun Sahin; Pedram Hamrah
Journal:  Ophthalmol Eye Dis       Date:  2012-04-19
  8 in total

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