Literature DB >> 678442

Survival of human 51Cr erythrocytes in guinea-pigs.

A N Azikiwe, O Castro, G W Obaldiston, S C Finch.   

Abstract

A guinea-pig model for study of the survival of human erythrocytes has been developed. The T1/2 survival of human erythrocytes in guinea pigs treated with ethyl palmitate and cobra venom factor is about 3 days. This model is particularly suited to the study of the pathogenesis and therapy of certain intrinsic red cell disorders, such as sickle-cell disease.

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Year:  1978        PMID： 678442      PMCID： PMC2041355     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  8 in total

Review 1.  The development of a heterologous transfusion technique: application to sickle cell disease.

Authors:  S C Finch; O Castro; J Orlin; M W Rosen; L Aponte
Journal:  Conn Med       Date:  1974-07

2.  Sickle cell resistance to in vivo hypoxia.

Authors:  O Castro; S C Finch; G Osbaldiston
Journal:  Nature       Date:  1974-10-18       Impact factor: 49.962

3.  Mechanism of ethyl palmitate and cobra venom factor enhancement of heterologous erythrocyte survival.

Authors:  O Castro; M W Rosen; S C Finch; P J Mulrow
Journal:  Proc Soc Exp Biol Med       Date:  1974-10

4.  Correction of the permeability defect in hereditary stomatocytosis by dimethyl adipimidate.

Authors:  W C Mentzer; B H Lubin; S Emmons
Journal:  N Engl J Med       Date:  1976-05-27       Impact factor: 91.245

5.  Survival of human sickle-cell erythrocytes in heterologous species: response to variations in oxygen tension.

Authors:  O Castro; J Orlin; M W Rosen; S C Finch
Journal:  Proc Natl Acad Sci U S A       Date:  1973-08       Impact factor: 11.205

6.  Oxygen-dependent circulation of sickle erythrocytes.

Authors:  O Castro; G W Osbaldiston; L Aponte; R Roth; J Orlin; S C Finch
Journal:  J Lab Clin Med       Date:  1976-11

7.  The effects of a cobra venom factor and ethyl palmitate on the prolongation of survival of heterologous erythrocytes.

Authors:  M C Wright; R A Nelson; S C Finch
Journal:  Yale J Biol Med       Date:  1970-12

8.  The effect of hemoglobin carbamylation on the survival of human sickle cell erythrocytes in rats.

Authors:  O Castro; J Orlin; S C Finch
Journal:  Yale J Biol Med       Date:  1974-03
  8 in total

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