| Literature DB >> 6782842 |
Abstract
The antimalarial drugs amodiaquine, quinacrine and chloroquine inhibit the catabolism of putrescine by the rat. Amodiaquine, the most potent of the three, does so in a dose-dependent fashion. This is attributed to the action in vivo of the drugs on diamine oxidase, an enzyme that is inhibited by them in vitro.Entities:
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Year: 1980 PMID: 6782842 DOI: 10.1007/BF01968035
Source DB: PubMed Journal: Agents Actions ISSN: 0065-4299