Literature DB >> 6782675

Regression of aflatoxin B1-induced hepatocellular carcinomas by reduced glutathione.

A M Novi.   

Abstract

Reduced glutathione administered to rats bearing aflatoxin B1-induced liver tumors caused regression of tumor growth and resulted in survival of the animals. since glutathione is a harmless natural product, it merits further investigation as a potential antitumor drug for humans.

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Year:  1981        PMID： 6782675     DOI： 10.1126/science.6782675

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  14 in total

Review 1.  New careers for antioxidants.

Authors:  Douglas E Brash; P A Havre
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-21       Impact factor: 11.205

2.  Unlabeled hemoglobin adducts of 4,4'-methylenebis (2-chloroaniline) in rats and guinea pigs.

Authors:  T H Chen; B I Kuslikis; W E Braselton
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

3.  Postoperative recurrence of hepatocellular carcinoma.

Authors:  T Nagao; S Inoue; F Yoshimi; M Sodeyama; Y Omori; T Mizuta; N Kawano; Y Morioka
Journal:  Ann Surg       Date:  1990-01       Impact factor: 12.969

4.  Active oxygen acts as a promoter of transformation in mouse embryo C3H/10T1/2/C18 fibroblasts.

Authors:  R Zimmerman; P Cerutti
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

5.  Influence of a prolonged treatment with disulfiram and D(-)penicillamine on nitrosodiethylamine-induced biological and biochemical effects in rats. I. Investigations on the drug metabolizing system.

Authors:  B Bertram; E Frei; H R Scherf; J Schuhmacher; A M Tacchi; M Wiessler
Journal:  J Cancer Res Clin Oncol       Date:  1985       Impact factor: 4.553

Review 6.  Hepatitis B virus infection. Current concepts of chronicity and immunity.

Authors:  G N Vyas; H E Blum
Journal:  West J Med       Date:  1984-05

7.  The effect of antioxidants on MNNG-induced stomach carcinogenesis in rats.

Authors:  R M Balansky; P M Blagoeva; Z I Mircheva; I Stoitchev; I Chernozemskí
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

8.  Oral supplementation with liposomal glutathione elevates body stores of glutathione and markers of immune function.

Authors:  R Sinha; I Sinha; A Calcagnotto; N Trushin; J S Haley; T D Schell; J P Richie
Journal:  Eur J Clin Nutr       Date:  2017-08-30       Impact factor: 4.016

9.  Leakage of glutathione from bacterial cells caused by inhibition of gamma-glutamyltranspeptidase.

Authors:  R Nakayama; H Kumagai; T Tochikura
Journal:  Appl Environ Microbiol       Date:  1984-04       Impact factor: 4.792

Review 10.  An overview of aflatoxicosis of poultry: its characteristics, prevention and reduction.

Authors:  R R Dalvi
Journal:  Vet Res Commun       Date:  1986-11       Impact factor: 2.459
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